Di-tert-butyl malonate
Di-tert-butyl malonate (CAS: 541-16-2) is an organic ester with the linear formula (CH3)3COCOCH2COOC(CH3)3 and a molecular weight of 216.27 g/mol. This compound serves as a valuable building block in organic synthesis. It has been utilised in complex total synthesis projects and as a precursor in materials science for depositing thin films via metal-organic chemical vapour deposition.
Organic Synthesis Building Block
Di-tert-butyl malonate functions as a versatile intermediate in the synthesis of complex organic molecules. Its structure allows for various derivatizations, making it useful in multi-step synthetic routes.
Materials Science Precursor
This compound has been employed as a precursor in metal-organic chemical vapour deposition (MOCVD) processes. It is specifically noted for its use in the deposition of hafnium oxide (HfO2) and zirconium oxide (ZrO2) thin films.
Pharmaceutical Intermediate
As a malonate ester derivative, Di-tert-butyl malonate can be a key component in the synthesis pathway for certain pharmaceutical compounds, contributing to the development of active pharmaceutical ingredients.
| Molecular weight | 216.27 |
|---|---|
| Linear formula | (CH3)3COCOCH2COOC(CH3)3 |
| Assay | 98% |
| Boiling point | 110-111 °C/22 mmHg(lit.) |
| Density | 0.966 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.418(lit.) |
| Application | Di-tert-butyl malonate was used in total synthesis of (+/−)-actinophyllic acid1. It was also employed as precursor for metal-organic chemical vapor deposition of HfO2 and ZrO2 thin films2. |
| Melting point | −7-−6 °C(lit.) |
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 89 °C / 192.2 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Di-tert-butyl malonate used for?
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Di-tert-butyl malonate is used as a building block in organic synthesis, including total synthesis of complex molecules like actinophyllic acid, and as a precursor for thin film deposition in materials science.
What is the CAS number and chemical formula for Di-tert-butyl malonate?
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The CAS number is 541-16-2 and the linear formula is (CH3)3COCOCH2COOC(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Di-tert-butyl malonate with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
What are the safety and handling considerations for Di-tert-butyl malonate?
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Di-tert-butyl malonate is combustible and requires appropriate handling. Personal protective equipment, including eyeshields and gloves, is recommended. Refer to the safety data sheet for comprehensive handling and hazard information.
How is Di-tert-butyl malonate packed, shipped, and exported?
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Di-tert-butyl malonate is typically packed securely for transport according to international regulations. Tech Serve Solutions is an experienced global exporter of fine chemicals.
How can I request a sample or quote for Di-tert-butyl malonate?
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To request a sample or a quote for Di-tert-butyl malonate, please contact our sales department through the website or by phone.
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