D-Leucine
D-Leucine (CAS: 328-38-1) is a non-proteinogenic amino acid derivative with the linear formula (CH3)2CHCH2CH(NH2)CO2H and a molecular weight of 131.17 g/mol. Supplied by Tech Serve Solutions at a purity of 99%, it exhibits specific optical activity. D-Leucine is a valuable chiral building block utilised in chemical synthesis, peptide chemistry, and biochemical research, offering unique properties due to its D-configuration.
- IUPAC
- (R)-2-Amino-4-methylpentanoic acid
Chiral Synthesis
D-Leucine serves as a key chiral synthon in the asymmetric synthesis of complex organic molecules and pharmaceutical intermediates. Its defined stereochemistry is crucial for creating enantiomerically pure target compounds.
Peptide Chemistry
Incorporated into synthetic peptides, D-Leucine can confer altered conformational stability, enzymatic resistance, and receptor binding properties compared to its L-enantiomer. This makes it useful for developing novel peptide-based therapeutics or research tools.
Chemical Biology Research
As a non-natural amino acid, D-Leucine finds application in probing biological systems and protein structures. It can be used to study enzyme mechanisms or to design peptides with modified biological activities.
| Molecular weight | 131.17 |
|---|---|
| Linear formula | (CH3)2CHCH2CH(NH2)CO2H |
| Assay | 99% |
| Optical activity | [α]23/D −14.7°, c = 2 in 5 M HCl |
| Optical purity | ee: 97% (GLC) |
| Melting point | >300 °C(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Leucine used for?
+
D-Leucine is primarily utilised as a chiral building block in chemical synthesis, particularly for preparing enantiomerically pure compounds, and in peptide chemistry to modify peptide properties.
What are the CAS number and formula for D-Leucine?
+
The CAS number for D-Leucine is 328-38-1. Its linear formula is (CH3)2CHCH2CH(NH2)CO2H.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies D-Leucine with an assay of 99%. This product is suitable for research and synthesis applications; TSS does not represent it as USP, BP, or EP grade.
How should D-Leucine be handled safely?
+
D-Leucine is classified under GHS with specific hazard statements. Handle with appropriate personal protective equipment in a well-ventilated area, avoiding dust formation and contact with skin, eyes, and clothing. Refer to the Safety Data Sheet for full details.
How is D-Leucine packed, shipped, and exported?
+
D-Leucine is carefully packed to ensure stability during transit. Tech Serve Solutions has extensive experience in exporting chemicals globally, adhering to all relevant international shipping regulations.
How can I request a sample or quote for D-Leucine?
+
To request a sample or a quotation for D-Leucine, please contact our sales department through the website or via direct email, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis