2-Thiophenecarboxylic acid
2-Thiophenecarboxylic acid (CAS: 527-72-0) is a key heterocyclic building block with the molecular formula C5H4O2S and a molecular weight of 128.15 g/mol. This compound is valuable in chemical synthesis, particularly for creating more complex molecules. It is widely utilised in research and development laboratories for organic synthesis and medicinal chemistry applications.

Organic Synthesis Intermediate
2-Thiophenecarboxylic acid serves as a versatile intermediate in the synthesis of various organic compounds. Its reactive carboxylic acid group and thiophene ring allow for diverse chemical transformations.
Heterocyclic Chemistry
As a thiophene derivative, it is a fundamental building block in heterocyclic chemistry. It is employed in the construction of novel heterocyclic systems with potential applications in materials science and pharmaceuticals.
Pharmaceutical Research
This compound is utilised in medicinal chemistry research for the development of new drug candidates. The thiophene moiety is present in several biologically active molecules.
| Molecular weight | 128.15 |
|---|---|
| Empirical formula | C5H4O2S |
| Assay | 98% |
| Boiling point | 260 °C(lit.) |
| Melting point | 125-127 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Thiophenecarboxylic acid used for?
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2-Thiophenecarboxylic acid is primarily used as an intermediate in organic synthesis, particularly within heterocyclic and pharmaceutical research.
What is the CAS number and chemical formula for 2-Thiophenecarboxylic acid?
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The CAS number is 527-72-0 and the empirical formula is C5H4O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Thiophenecarboxylic acid with an assay of 98%. This product is not represented as USP, BP, or EP grade.
How should 2-Thiophenecarboxylic acid be handled?
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Handle 2-Thiophenecarboxylic acid with appropriate personal protective equipment, including a dust mask (N95 US recommended), eyeshields, and gloves, in a well-ventilated area. It is classified as a warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Does TSS export 2-Thiophenecarboxylic acid?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Thiophenecarboxylic acid.
How can I request a sample or quote for 2-Thiophenecarboxylic acid?
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To request a sample or quote, please contact the TSS sales department through the website or by phone.
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