2-Thiophenecarbonyl chloride
2-Thiophenecarbonyl chloride (CAS: 5271-67-0) is a heterocyclic organic compound with the molecular formula C5H3ClOS and a molecular weight of 146.59 g/mol. This reactive acid chloride is a valuable intermediate in organic synthesis, particularly for the preparation of thiophene derivatives. It is commonly employed in the construction of more complex molecules for research and development, with applications spanning pharmaceuticals and materials science.
- IUPAC
- α-Thenoyl chloride
- Synonyms
- α-Thenoyl chloride
Pharmaceutical Intermediate
2-Thiophenecarbonyl chloride serves as a key building block in the synthesis of various pharmaceutical agents. Its reactive nature allows for the introduction of the thiophene moiety into drug candidates, influencing their pharmacological properties.
Chemical Synthesis Reagent
As a reactive acylating agent, it is widely utilized in academic and industrial research for the creation of novel organic compounds. It facilitates the formation of amides, esters, and ketones containing a thiophene ring.
Materials Science Research
The thiophene unit is a fundamental component in conductive polymers and organic electronic materials. 2-Thiophenecarbonyl chloride can be used in the derivatization of monomers for advanced material applications.
| Molecular weight | 146.59 |
|---|---|
| Empirical formula | C5H3ClOS |
| Assay | 97% |
| Boiling point | 206-208 °C(lit.) |
| Density | 1.371 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.590(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 91 °C / 195.8 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Thiophenecarbonyl chloride used for?
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2-Thiophenecarbonyl chloride is primarily used as a building block in organic synthesis, particularly for preparing thiophene-containing compounds for pharmaceutical research, chemical synthesis, and materials science.
What are the CAS number and chemical formula for 2-Thiophenecarbonyl chloride?
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The CAS number is 5271-67-0, and its empirical formula (Hill notation) is C5H3ClOS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Thiophenecarbonyl chloride with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the specifications.
How should 2-Thiophenecarbonyl chloride be handled safely?
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2-Thiophenecarbonyl chloride is classified as corrosive and causes severe skin burns and eye damage (H314). Handle with extreme care, using full personal protective equipment including chemical-resistant gloves, safety goggles, a face shield, and appropriate respiratory protection. Work in a well-ventilated area or fume hood.
How is 2-Thiophenecarbonyl chloride packed and shipped?
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2-Thiophenecarbonyl chloride is packed according to UN 3265 standards for corrosive liquid, acidic, organic, n.o.s., Class 8, Packing Group II. TSS exports globally, adhering to all relevant shipping regulations for hazardous materials.
How can I request a quote or sample for 2-Thiophenecarbonyl chloride?
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To request a quote or a sample of 2-Thiophenecarbonyl chloride, please contact our sales department through the website or by phone. We will respond promptly with pricing and availability.
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