2-Thiopheneacetonitrile
2-Thiopheneacetonitrile (CAS 20893-30-5), with the molecular formula C6H5NS and a molecular weight of 123.18 g/mol, is a versatile heterocyclic building block. This compound, characterised by its thiophene ring and nitrile group, serves as a key intermediate in organic synthesis. It is primarily utilised in the development of pharmaceuticals, agrochemicals, and advanced materials, owing to its reactivity and structural features that enable diverse chemical transformations.
- IUPAC
- 2-Thienylacetonitrile
Pharmaceutical Intermediates
2-Thiopheneacetonitrile is a valuable precursor in the synthesis of various active pharmaceutical ingredients (APIs). Its structure can be incorporated into molecules designed for a range of therapeutic applications.
Agrochemical Development
The compound finds application in the creation of novel agrochemicals, including pesticides and herbicides. Its heterocyclic nature can contribute to the biological activity of these agricultural products.
Material Science
As a building block, 2-Thiopheneacetonitrile can be used in the synthesis of specialised organic materials. This includes polymers and compounds with unique electronic or optical properties.
Organic Synthesis Reagent
It acts as a fundamental reagent in complex organic syntheses, facilitating the construction of intricate molecular architectures. Its nitrile group offers a convenient handle for further functionalisation.
| Molecular weight | 123.18 |
|---|---|
| Empirical formula | C6H5NS |
| Assay | ≥97.0% (GC) |
| Boiling point | 115-120 °C/22 mmHg(lit.)235-238 °C(lit.) |
| Density | 1.157 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.542(lit.)n20/D 1.542 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 102 °C / 215.6 °F |
| Transport (UN / ADR) | UN 3276 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Thiopheneacetonitrile used for?
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2-Thiopheneacetonitrile is primarily used as a building block and intermediate in organic synthesis, particularly for pharmaceuticals, agrochemicals, and material science applications.
What is the CAS number and formula for 2-Thiopheneacetonitrile?
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The CAS number for 2-Thiopheneacetonitrile is 20893-30-5, and its molecular formula is C6H5NS.
What grade and purity does Tech Serve Solutions supply for 2-Thiopheneacetonitrile?
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Tech Serve Solutions supplies 2-Thiopheneacetonitrile with an assay of ≥97.0% (GC). This product is supplied for research and development purposes; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should 2-Thiopheneacetonitrile be handled safely?
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2-Thiopheneacetonitrile is harmful if swallowed, in contact with skin, or if inhaled, and causes skin irritation, serious eye irritation, and respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Refer to the safety data sheet for comprehensive handling information.
How is 2-Thiopheneacetonitrile packed and shipped?
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2-Thiopheneacetonitrile is packed according to industry standards for chemical reagents and can be exported globally by Tech Serve Solutions. For specific packaging and shipping inquiries, please contact our sales team.
How can I request a sample or quote for 2-Thiopheneacetonitrile?
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To request a sample or a quote for 2-Thiopheneacetonitrile, please visit the product page on our website or contact our customer service department directly.
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