D-Hydroorotic acid
D-Hydroorotic acid (CAS: 5988-53-4), with the molecular formula C5H6N2O4 and a molecular weight of 158.11 g/mol, is a key chiral building block and heterocyclic compound. It serves as a valuable intermediate in chemical synthesis and asymmetric reactions. D-Hydroorotic acid is essential for researchers involved in the development of novel organic molecules and pharmaceutical intermediates, offering a specific stereochemical configuration for complex syntheses.
- IUPAC
- R-2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid,Dihydro-D-orotic acid

Asymmetric Synthesis
D-Hydroorotic acid is utilised as a chiral building block in asymmetric synthesis, enabling the stereoselective construction of complex molecules. Its defined stereochemistry is crucial for creating enantiomerically pure target compounds.
Chemical Synthesis Intermediate
This compound functions as an important intermediate in various chemical synthesis pathways. It is employed in the preparation of more complex organic structures and heterocyclic compounds.
Heterocyclic Chemistry
As a pyrimidine derivative, D-Hydroorotic acid is instrumental in heterocyclic chemistry research and development. It provides a foundational structure for synthesising a range of nitrogen-containing heterocycles.
| Molecular weight | 158.11 |
|---|---|
| Empirical formula | C5H6N2O4 |
| Assay | 98% |
| Optical activity | [α]20/D −33°, c = 1 in NaHCO3 |
| Melting point | 255 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Hydroorotic acid primarily used for?
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D-Hydroorotic acid is primarily used in asymmetric synthesis and as a chemical synthesis intermediate, particularly in heterocyclic and pyrimidine chemistry.
What are the CAS number and molecular formula for D-Hydroorotic acid?
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The CAS number for D-Hydroorotic acid is 5988-53-4, and its molecular formula is C5H6N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-Hydroorotic acid with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should D-Hydroorotic acid be handled safely?
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D-Hydroorotic acid is a Warning substance (GHS07) and is classified with hazards H315, H319, and H335. Safe handling requires wearing a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. Refer to the Safety Data Sheet for full details.
Is D-Hydroorotic acid a controlled substance?
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The provided data does not indicate that D-Hydroorotic acid is a controlled substance.
How is D-Hydroorotic acid packed and exported?
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D-Hydroorotic acid is carefully packed to ensure stability and integrity during transit. Tech Serve Solutions is an experienced global exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a quote or sample for D-Hydroorotic acid?
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To request a quote or sample of D-Hydroorotic acid, please contact our sales department through the TSS website or by phone.
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