D-Homoserine
D-Homoserine (CAS: 6027-21-0) is a non-proteinogenic amino acid characterised by a hydroxyl group on the gamma-carbon. Its linear formula is HOCH2CH2CH(NH2)CO2H and it has a molecular weight of 119.12 g/mol. Primarily utilised in chemical biology and synthesis, it serves as a key building block in peptide chemistry and for the creation of unnatural amino acid derivatives, offering unique structural and functional possibilities.
- IUPAC
- (R)-(+)-2-Amino-4-hydroxybutyric acid
- Synonyms
- (R)-(+)-2-Amino-4-hydroxybutyric acid
Chemical Biology Research
D-Homoserine is employed as a valuable tool in chemical biology for probing biological systems and developing novel biomolecules. Its structural similarity to natural amino acids allows for its incorporation into peptides and proteins to study structure-function relationships.
Peptide Synthesis
This unnatural amino acid derivative is instrumental in peptide chemistry, enabling the synthesis of modified peptides with enhanced stability, altered biological activity, or unique conformational properties. It is used to extend peptide chains beyond the standard 20 amino acids.
Custom Synthesis
D-Homoserine serves as a versatile intermediate in complex organic synthesis pathways. Its functional groups allow for diverse chemical modifications, making it a useful starting material for the creation of specialised compounds and advanced research chemicals.
Development of Unnatural Amino Acids
As a homo-amino acid, D-Homoserine contributes to the field of unnatural amino acid research. It can be used as a precursor or a model compound for synthesising and evaluating new amino acid analogues with potential therapeutic or diagnostic applications.
| Molecular weight | 119.12 |
|---|---|
| Linear formula | HOCH2CH2CH(NH2)CO2H |
| Melting point | 205 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Homoserine used for?
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D-Homoserine is primarily used in chemical biology and synthesis, particularly in peptide chemistry and the development of unnatural amino acid derivatives.
What is the CAS number and formula for D-Homoserine?
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The CAS number for D-Homoserine is 6027-21-0, and its linear formula is HOCH2CH2CH(NH2)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-Homoserine for research and development purposes. The specific grade and purity can be found on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade unless explicitly stated.
How should D-Homoserine be handled?
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D-Homoserine (CAS: 6027-21-0) requires careful handling. Personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
Is D-Homoserine classified as a controlled substance?
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Based on the provided data, D-Homoserine (CAS: 6027-21-0) is not indicated as a controlled substance.
How is D-Homoserine packed and shipped?
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D-Homoserine is available from Tech Serve Solutions, a global supplier and exporter. Packaging and shipping methods comply with international regulations for chemical transport.
How can I request a sample or quote for D-Homoserine?
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To request a sample or a quote for D-Homoserine (CAS: 6027-21-0), please contact our sales team through the Tech Serve Solutions website or via the provided contact details.
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