D-Histidine monohydrochloride monohydrate
D-Histidine monohydrochloride monohydrate (CAS: 6341-24-8), with the empirical formula C6H9N3O2 · HCl · H2O and a molecular weight of 209.63 g/mol, is a derivative of the amino acid histidine. It serves as a valuable reagent in chemical synthesis and biological research. This compound is particularly relevant in studies of cell biology, neuroscience, and peptide chemistry due to its role in neurotransmission and biological signalling pathways.
- IUPAC
- D-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride

Chemical Synthesis
D-Histidine monohydrochloride monohydrate is employed as a building block or reagent in the synthesis of more complex organic molecules and peptide chains. Its specific stereochemistry and functional groups make it useful for targeted chemical transformations.
Neuroscience Research
This compound is utilised in research related to neurotransmission and the functioning of the nervous system. It plays a role in understanding pathways involving histamine and related signalling molecules within the brain.
Biochemical Studies
As an amino acid derivative, it is used in various biochemical assays and studies investigating protein structure, function, and interactions. Its properties are relevant for understanding biological processes at the cellular level.
Cell Biology Applications
Researchers utilise D-Histidine monohydrochloride monohydrate in cell culture and experimental systems to probe cellular mechanisms, signalling pathways, and the effects of specific molecules on cell behaviour.
| Molecular weight | 209.63 |
|---|---|
| Empirical formula | C6H9N3O2 · HCl · H2O |
| Assay | ≥98% (TLC) |
| Melting point | 254 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HRH1(3269)mouse ... HRH1(15465)rat ... HRH1(24448) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Histidine monohydrochloride monohydrate used for?
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D-Histidine monohydrochloride monohydrate is used in chemical synthesis, neuroscience research, biochemical studies, and cell biology applications.
What are the CAS number and formula for D-Histidine monohydrochloride monohydrate?
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The CAS number is 6341-24-8 and the formula is C6H9N3O2 · HCl · H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-Histidine monohydrochloride monohydrate with a purity of ≥98% (TLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should D-Histidine monohydrochloride monohydrate be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound is classified with a WGK Germany of 3, indicating significant hazard to water.
How is D-Histidine monohydrochloride monohydrate packed and exported?
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D-Histidine monohydrochloride monohydrate is carefully packed to ensure stability during transport and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for D-Histidine monohydrochloride monohydrate?
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To request a sample or quote, please contact our sales team through the website or by phone.
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