D-Histidine
D-Histidine (CAS: 351-50-8; C6H9N3O2) is a stereoisomer of the amino acid histidine. It presents as a chiral molecule, a derivative of histidine with the D-configuration at the alpha-carbon. D-Histidine serves as a valuable building block in chemical synthesis, particularly in peptide chemistry and biochemical research. Its specific stereochemistry makes it distinct from its L-enantiomer, offering unique properties for specialised applications in chemical biology.
- IUPAC
- (R)-2-Amino-3-(4-imidazolyl)propionic acid,D-α-Amino-β-(4-imidazolyl)propionic acid
Peptide Synthesis
D-Histidine is utilized as a non-proteinogenic amino acid in the synthesis of peptides, allowing for the creation of novel peptide structures with modified biological or chemical properties. This enables the study of structure-activity relationships and the development of peptidomimetics.
Biochemical Research
As a stereoisomer of a common amino acid, D-Histidine is employed in various biochemical research applications. It can be used to investigate enzymatic pathways, protein folding, and the effects of unnatural amino acids on biological systems.
Chemical Biology
D-Histidine finds application in chemical biology for probing biological mechanisms. Its incorporation into molecular probes or labelled compounds can help elucidate complex biological processes and interactions at the molecular level.
Organic Synthesis
This compound serves as a chiral building block in organic synthesis. Its distinct stereochemistry is valuable for constructing complex chiral molecules and intermediates used in the development of new pharmaceuticals and materials.
| Molecular weight | 155.15 |
|---|---|
| Empirical formula | C6H9N3O2 |
| Assay | 98% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CA1(759), CA2(760) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Histidine used for?
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D-Histidine is primarily used in peptide synthesis, biochemical research, chemical biology, and as a chiral building block in organic synthesis.
What are the CAS number and formula for D-Histidine?
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The CAS number for D-Histidine is 351-50-8, and its empirical formula is C6H9N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-Histidine with an assay of 98%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated otherwise in the product documentation.
What are the safety and handling precautions for D-Histidine?
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Handling D-Histidine requires personal protective equipment including eyeshields and gloves. A respirator filter such as type N95 (US) or type P1 (EN143) is recommended. The WGK Germany is 1, indicating low hazard.
Is D-Histidine a controlled substance?
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The provided data does not indicate that D-Histidine is a controlled substance.
How can I request a sample or quote for D-Histidine?
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To request a sample or a quotation for D-Histidine, please contact our sales team through the website or by direct inquiry.
How is D-Histidine packed, shipped, and exported?
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D-Histidine is carefully packed to maintain its integrity during transit. Tech Serve Solutions is experienced in global exporting of chemical products, adhering to all necessary regulations for safe and compliant shipment.
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