D-Homophenylalanine
D-Homophenylalanine (CAS: 82795-51-5) is an unnatural amino acid derivative with the molecular formula C6H5CH2CH2CH(NH2)CO2H and a molecular weight of 179.22 g/mol. Characterised by its phenylpropyl side chain, it serves as a valuable building block in peptide chemistry and chemical synthesis. This compound is widely utilised in biochemical research and the development of novel chemical entities within the fields of chemical biology.
- IUPAC
- (R)-2-Amino-4-phenylbutyric acid

Peptide Synthesis
D-Homophenylalanine can be incorporated into peptide sequences to modify their structure, stability, and biological activity. Its inclusion can introduce conformational constraints or alter receptor binding properties compared to natural amino acids.
Chemical Biology Research
As an unnatural amino acid, it is employed in chemical biology to probe protein function, develop new diagnostic tools, or create novel biomaterials. Researchers utilise it to investigate structure-activity relationships and explore non-natural biological systems.
Drug Discovery and Development
This compound serves as a chiral intermediate in the synthesis of complex organic molecules and potential pharmaceutical agents. Its unique structure allows for the creation of novel drug candidates with tailored pharmacological profiles.
Material Science
D-Homophenylalanine can be used as a monomer or building block in the development of advanced polymers and materials. Its incorporation can impart specific properties such as biocompatibility or altered physical characteristics.
| Molecular weight | 179.22 |
|---|---|
| Linear formula | C6H5CH2CH2CH(NH2)CO2H |
| Assay | 98% |
| Optical activity | [α]19/D −45°, c = 1 in 3 M HCl |
| Melting point | >300 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Homophenylalanine used for?
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D-Homophenylalanine is primarily used in peptide synthesis, chemical biology research, and as an intermediate in the development of novel pharmaceuticals and materials due to its unique unnatural amino acid structure.
What are the CAS number and chemical formula for D-Homophenylalanine?
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The CAS number for D-Homophenylalanine is 82795-51-5, and its chemical formula is C6H5CH2CH2CH(NH2)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-Homophenylalanine with an assay of 98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should D-Homophenylalanine be handled safely?
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Handle D-Homophenylalanine with appropriate personal protective equipment, including eyeshields, gloves, and a P1 (EN143) or N95 (US) respirator filter. Refer to the Safety Data Sheet for comprehensive handling instructions. It has a high melting point of over 300 °C.
Is D-Homophenylalanine a controlled substance?
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The provided data does not indicate that D-Homophenylalanine is a controlled substance.
How is D-Homophenylalanine typically shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including D-Homophenylalanine, adhering to international shipping and export regulations for chemical products.
How can I request a quote or sample of D-Homophenylalanine?
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To request a quote or sample of D-Homophenylalanine, please contact our sales department through the TSS website or by phone.
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