Cetirizine dihydrochloride

CAS 83881-52-1C21H25ClN2O3 · 2HClBiochemicals & Reagents

Cetirizine dihydrochloride (CAS: 83881-52-1), with the molecular formula C21H25ClN2O3 · 2HCl and a molecular weight of 461.81 g/mol, is a white solid. It functions as a potent antihistamine, primarily used in pharmaceutical research and development. Its properties make it a valuable compound for investigating histamine receptor interactions and developing new therapeutic agents. TSS supplies this chemical for laboratory and research applications.

IUPAC: [2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride

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Cetirizine dihydrochloride (C21H25ClN2O3 · 2HCl) — chemical structure, CAS 83881-52-1; Life Science, fine chemical supplied by Tech Serve Solutions

AntagonistsBioactive Small MoleculesBiochemicals and ReagentsC-CHCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesHistaminergicsHistaminergics - Antagonists

01 /Applications

Pharmaceutical Research

Used as a research chemical in the development of new antihistamine drugs and related therapeutics. It serves as a reference standard for analytical method development and validation.

Biochemical Studies

Investigates histamine H1 receptor antagonism and its effects on cellular signaling pathways. Useful for understanding allergic responses and related physiological processes.

Drug Discovery

Employed in screening assays and structure-activity relationship studies for novel drug candidates targeting histamine receptors.

02 /Properties

Molecular weight	461.81
Empirical formula	C21H25ClN2O3 · 2HCl
Assay	≥98% (HPLC)
Form	solid
Colour	white
Solubility	H2O: >10 mg/mL

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

83881-52-1

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Cetirizine dihydrochloride used for?

Cetirizine dihydrochloride is used as a research chemical in pharmaceutical and biochemical studies, particularly for investigating histamine H1 receptor antagonism and in drug discovery efforts.

What is the CAS number and chemical formula for Cetirizine dihydrochloride?

The CAS number is 83881-52-1, and the chemical formula is C21H25ClN2O3 · 2HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Cetirizine dihydrochloride with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Cetirizine dihydrochloride be handled?

Cetirizine dihydrochloride is classified as harmful if swallowed (H302). Handle with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, face shields, and gloves, in a well-ventilated area.

Is Cetirizine dihydrochloride a controlled substance?

The provided data does not indicate that Cetirizine dihydrochloride is a controlled substance.

How is Cetirizine dihydrochloride packed and exported?

Cetirizine dihydrochloride is typically supplied as a white solid. TSS ensures secure packaging suitable for international export of research chemicals.