XTT sodium salt
XTT sodium salt (CAS: 111072-31-2), with the empirical formula C22H16N7NaO13S2 and a molecular weight of 673.52 g/mol, is a tetrazolium salt used as a colorimetric reagent. It is primarily employed in cell-based assays to measure cell viability, proliferation, and cytotoxicity. This water-soluble powder is suitable for cell culture applications, facilitating quantitative analysis of cellular metabolic activity. It is a key reagent in various biological research fields, including stem cell biology and drug discovery.
- IUPAC
- 2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt
Cell Viability and Proliferation Assays
XTT sodium salt is widely used in colorimetric assays to assess cell metabolic activity, providing a quantitative measure of cell viability and proliferation. It is often used in conjunction with phenazine methosulfate (PMS) to detect cellular reduction.
Cytotoxicity Screening
This reagent is valuable for screening cancer cell lines and evaluating the cytotoxic effects of various compounds. Its ability to form a soluble formazan product simplifies data interpretation in cytotoxicity studies.
Stem Cell Biology Research
XTT sodium salt serves as a fluorescent reagent for the in vivo and in vitro tracking of stem cells. It is also applied in general staining and dye applications within stem cell research.
Antimicrobial Susceptibility Testing
The assay has been employed in testing the antimicrobial susceptibility of bacterial strains, such as staphylococci, and in researching microbial biofilm formation.
| Molecular weight | 673.52 |
|---|---|
| Empirical formula | C22H16N7NaO13S2 |
| Assay | ≥90% |
| Form | powder |
| Solubility | H2O: soluble2.5 mg/mL (hot) |
| Storage temperature | 2-8°C |
| Application | XTT has been used in conjunction with phenazine methosulfate (PMS) to screen human cancer cell lines.1 The tetrazolium dye has also been used to study fungal cell damage,2 in testing antimicrobial susceptibility of staphylococci,3 and in Candida biofilm research.4 Limitations to the XTT assay have been reported.5 |
| Suitability | suitable for cell culture |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioReagent |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is XTT sodium salt used for?
+
XTT sodium salt is used in cell-based assays to measure cell viability, proliferation, and cytotoxicity. It is also employed in stem cell tracking, antimicrobial susceptibility testing, and biofilm research.
What are the CAS number and formula for XTT sodium salt?
+
The CAS number for XTT sodium salt is 111072-31-2, and its empirical formula is C22H16N7NaO13S2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies XTT sodium salt with an assay of ≥90%, suitable for cell culture. This product is supplied for research purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should XTT sodium salt be handled and stored?
+
Handle XTT sodium salt with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter. Store the product at 2-8°C.
Is XTT sodium salt a controlled substance?
+
The provided data does not indicate that XTT sodium salt is a controlled substance.
How can I request a quote or sample for XTT sodium salt?
+
Please contact Tech Serve Solutions via our website or sales representatives to request a quote or a sample for XTT sodium salt.
How is XTT sodium salt packaged and shipped?
+
XTT sodium salt is typically supplied as a powder and can be shipped internationally by Tech Serve Solutions. Specific packaging details are available upon request.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis