Cerulenin

CAS 17397-89-6C12H17NO3Biochemicals & Reagents

Cerulenin (CAS 17397-89-6), with the molecular formula C12H17NO3, is a natural antibiotic isolated from Cephalosporium caerulens. It is recognised for its potent inhibitory effects on fatty acid synthesis and other lipogenic enzymes. This compound is a valuable tool in biochemical research, particularly for studying lipid metabolism and related cellular processes.

IUPAC: (2R,3S,E,E)-2,3-Epoxy-4-oxo-7,10-dodecadienamide

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Cerulenin (C12H17NO3) — chemical structure, CAS 17397-89-6; Life Science, fine chemical supplied by Tech Serve Solutions

AntibioticsAntibiotics A to ZAntibiotics A-FAntibiotics by ApplicationAntifungalBioactive Small MoleculesBiochemicals and ReagentsC-CHCancer MetabolismCancer Research

01 /Applications

Fatty Acid Synthesis Inhibition

Cerulenin is a potent inhibitor of fatty acid synthetase (FASN) and other enzymes involved in lipogenesis. It is widely used in research to elucidate the mechanisms of lipid metabolism and the regulation of fatty acid production.

Biochemical Research Tool

As a bioactive small molecule, Cerulenin serves as a critical reagent for studying cancer metabolism, cell signalling, and various cellular processes affected by lipid biosynthesis. Its specific inhibitory action makes it useful for dissecting metabolic pathways.

Antifungal and Antineoplastic Research

While primarily known for its impact on fatty acid synthesis, Cerulenin has also been investigated for its antifungal properties and its potential as an antineoplastic agent in cancer research due to its interference with essential metabolic pathways.

02 /Properties

Molecular weight	223.27
Empirical formula	C12H17NO3
Assay	≥98% (HPLC)
Storage temperature	−20°C
Biological source	from Cephalosporium caerulens

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

17397-89-6

MDL number

MFCD00077686

PubChem substance

24892323

Beilstein registry

4140423

05 /Additional specifications

Gene Information	human ... FASN(2194)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Cerulenin used for?

Cerulenin is used in biochemical research to inhibit fatty acid synthesis and study lipid metabolism, cancer metabolism, cell signalling, and its antifungal and potential antineoplastic properties.

What is the CAS number and molecular formula for Cerulenin?

The CAS number for Cerulenin is 17397-89-6, and its molecular formula is C12H17NO3.

What grade and purity does Tech Serve Solutions supply for Cerulenin?

Tech Serve Solutions supplies Cerulenin with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.

How should Cerulenin be handled safely?

Cerulenin is classified as harmful if swallowed (H302). When handling, use a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation and avoid ingestion. Refer to the safety data sheet for comprehensive handling information.