Chelerythrine chloride
Chelerythrine chloride (CAS 3895-92-9) is a quaternary benzophenanthridine alkaloid, presenting as a yellow to orange powder. With a molecular weight of 383.82 g/mol and empirical formula C21H18ClNO4, it is primarily utilised in biochemical research as an enzyme inhibitor, particularly targeting protein kinase C. Its applications extend to cell biology and cell signaling studies, making it a valuable reagent for investigating cellular processes.
- IUPAC
- 1,2-Dimethoxy-N-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium chloride
- Synonyms
- 1,2-Dimethoxy-N-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium chloride
Enzyme Inhibition Studies
Chelerythrine chloride is widely employed as an inhibitor of protein kinase C (PKC) and other related kinases. This allows researchers to probe the role of these enzymes in various cellular signaling pathways.
Cell Biology Research
As a bioactive small molecule, it is used to investigate cellular functions, including cell proliferation, apoptosis, and differentiation. Its effects on cell cycle progression are a key area of study.
Neuroscience Research
The compound has found applications in neuroscience for studying cellular signaling mechanisms in neuronal cells and understanding its impact on neurotransmission and related processes.
Biochemical Reagent
Chelerythrine chloride serves as a valuable biochemical reagent for in vitro studies, providing a tool for researchers to modulate kinase activity and explore its downstream effects.
| Molecular weight | 383.82 |
|---|---|
| Empirical formula | C21H18ClNO4 |
| Assay | ≥95% (TLC) |
| Form | powder |
| Colour | yellow to orange |
| Solubility | DMSO: soluble2 mg/mL |
| Storage temperature | −20°C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chelerythrine chloride used for?
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Chelerythrine chloride is primarily used as an enzyme inhibitor, particularly for protein kinase C (PKC), in biochemical and cell biology research. It is also employed in neuroscience studies to investigate cellular signaling pathways.
What is the CAS number and formula for Chelerythrine chloride?
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The CAS number for Chelerythrine chloride is 3895-92-9, and its empirical formula is C21H18ClNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chelerythrine chloride with an assay of ≥95% (TLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Chelerythrine chloride be handled and stored?
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Chelerythrine chloride is a warning substance requiring careful handling. It is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation. Store at −20°C as indicated by the product data.
Is Chelerythrine chloride a controlled substance?
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Based on the provided safety data, Chelerythrine chloride is not listed as a controlled substance. However, regulations can vary by jurisdiction.
How is Chelerythrine chloride packed, shipped, and exported?
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Chelerythrine chloride is typically supplied as a powder and exported according to international shipping regulations for chemical reagents. Specific packaging details will be provided upon inquiry.
How can I request a sample or a quote for Chelerythrine chloride?
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To request a sample or a quote for Chelerythrine chloride, please contact our sales team through the website or via direct inquiry, providing your specific requirements and shipping details.
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