Brucine
Brucine (CAS: 357-57-3), with the molecular formula C23H26N2O4 and a molecular weight of 394.46 g/mol, is a crystalline alkaloid. It is known for its potent biological activity and serves as a crucial reagent in chemical synthesis. Brucine finds significant application as a chiral resolving agent in asymmetric synthesis, enabling the separation of enantiomers and the preparation of optically pure compounds. Its properties make it valuable for researchers and manufacturers requiring high stereochemical control.
- IUPAC
- 10,11-Dimethoxystrychnine
- Synonyms
- 10,11-Dimethoxystrychnine
Chiral Resolution Agent
Brucine is widely employed for the resolution of racemic mixtures, particularly for optically active acids. Its ability to form diastereomeric salts with specific optical rotation allows for the separation of enantiomers.
Asymmetric Synthesis
As a chiral building block, Brucine is utilised in various asymmetric synthesis pathways. It aids in the stereoselective formation of complex molecules, contributing to the development of chiral pharmaceuticals and fine chemicals.
Chemical Synthesis Reagent
Beyond chiral applications, Brucine acts as a versatile reagent in general chemical synthesis. It can be a starting material or intermediate in the production of various organic compounds.
| Molecular weight | 394.46 |
|---|---|
| Empirical formula | C23H26N2O4 |
| Assay | 98% |
| Grade | anhydrous |
| Optical activity | [α]20/D −118°, c = 2.5 in chloroform |
| Melting point | 175-178 °C (dec.)(lit.) |
Hazard statements
- H300Fatal if swallowed
- H330Fatal if inhaled
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P273Avoid release to the environment
- P284Wear respiratory protection
- P301IF SWALLOWED
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1570 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/28-52/53 |
| Safety statements (S) | 13-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Brucine primarily used for?
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Brucine (CAS: 357-57-3, Formula: C23H26N2O4) is primarily used as a chiral resolving agent in asymmetric synthesis to separate enantiomers and as a reagent in general chemical synthesis.
What is the CAS number and molecular formula for Brucine?
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The CAS number for Brucine is 357-57-3, and its molecular formula is C23H26N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Brucine with an assay of 98% and an anhydrous grade. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the main safety concerns when handling Brucine?
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Brucine is acutely toxic if swallowed or inhaled (H300, H330) and is harmful to aquatic life with long-lasting effects (H412). Extreme caution and appropriate personal protective equipment, including respiratory protection, gloves, and eye/face protection, are essential. Follow all safety precautions detailed in the Safety Data Sheet.
Is Brucine a controlled substance?
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While not explicitly listed as a controlled substance in all jurisdictions, Brucine is toxic and should be handled with extreme care. Its potential misuse warrants strict adherence to regulations and responsible procurement practices.
How is Brucine packed, shipped, and exported?
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Brucine is carefully packed according to international shipping regulations for hazardous materials. Tech Serve Solutions, as a specialist global supplier and exporter, ensures compliant packaging and documentation for worldwide distribution.
How can I request a sample or quote for Brucine?
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To request a sample or a quotation for Brucine, please contact our sales team directly through the website or by phone, providing your specific requirements and delivery details.
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