Brucine hydrate
Brucine hydrate (CAS: 5892-11-5), with the empirical formula C23H26N2O4 · xH2O and an anhydrous molecular weight of 394.46 g/mol, is a naturally occurring alkaloid. It is primarily recognised for its utility as a chiral resolving agent in asymmetric synthesis and chemical production. This compound serves as a valuable chiral building block for complex molecule synthesis, facilitating the separation of enantiomers in various chemical processes.
Chiral Resolution Reagent
Brucine hydrate is extensively employed in the resolution of racemic mixtures, enabling the separation of enantiomers. Its chiral nature allows it to form diastereomeric salts with chiral acids, facilitating separation through crystallisation.
Asymmetric Synthesis
In asymmetric synthesis, brucine hydrate acts as a chiral auxiliary or catalyst precursor. It contributes to the stereoselective formation of chiral molecules, which is crucial in the pharmaceutical and fine chemical industries.
Chemical Building Block
As a complex organic molecule derived from Strychnos nux-vomica seeds, brucine hydrate can be used as a starting material or intermediate in the synthesis of more intricate chemical structures.
| Molecular weight | 394.46 (anhydrous basis) |
|---|---|
| Empirical formula | C23H26N2O4 · xH2O |
| Grade | technical grade |
| Optical activity | [α]20/D −67°, c = 1.3 in ethanol |
| Melting point | 177-180 °C(lit.) |
Hazard statements
- H300Fatal if swallowed
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P273Avoid release to the environment
- P284Wear respiratory protection
- P301IF SWALLOWED
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 1570 6.1 / PGI |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/28-52/53 |
| Safety statements (S) | 13-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Brucine hydrate used for?
+
Brucine hydrate is primarily used as a chiral resolving agent for separating enantiomers, in asymmetric synthesis as a chiral building block, and in the chemical synthesis of complex molecules.
What are the CAS number and formula for Brucine hydrate?
+
The CAS number for Brucine hydrate is 5892-11-5, and its empirical formula is C23H26N2O4 · xH2O.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Brucine hydrate in technical grade. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
What are the safety considerations for handling Brucine hydrate?
+
Brucine hydrate is classified as acutely toxic (Danger, H300 + H330) and harmful to aquatic life with long-lasting effects (H412). Handle with extreme caution, using appropriate personal protective equipment (P260, P264, P273, P284, P301 + P310, P310) in a well-ventilated area. Avoid release to the environment (P273).
Does Tech Serve Solutions export Brucine hydrate?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Brucine hydrate.
How can I request a quote or sample for Brucine hydrate?
+
To request a quote or sample for Brucine hydrate, please contact our sales team through the website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis