3-Formyl-4-methoxyphenylboronic acid

CAS 121124-97-8HCOC6H3(OCH3)B(OH)2Chemical Synthesis

3-Formyl-4-methoxyphenylboronic acid (CAS 121124-97-8) is a specialised organic compound with the linear formula HCOC6H3(OCH3)B(OH)2 and a molecular weight of 179.97 g/mol. This aryl boronic acid serves as a valuable building block in organic synthesis. It is particularly useful as a reactant in copper(I)-mediated cyanation, Suzuki-Miyaura cross-coupling reactions, and the preparation of diverse biologically and pharmacologically relevant molecules.

IUPAC: 3-Formyl-4-methoxybenzeneboronic acid,5-Dihydroxyboryl-2-methoxybenzaldehyde
Synonyms: 3-Formyl-4-methoxybenzeneboronic acid5-Dihydroxyboryl-2-methoxybenzaldehyde

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3-Formyl-4-methoxyphenylboronic acid (HCOC6H3(OCH3)B(OH)2) — chemical structure, CAS 121124-97-8; Chemistry, fine chemical supplied by Tech Serve Solutions

AldehydesAryl Boronic AcidsBoronic AcidsBuilding BlocksCarbonyl CompoundsChemical SynthesisOrganic Building Blocks

01 /Applications

Suzuki-Miyaura Cross-Coupling Reactions

3-Formyl-4-methoxyphenylboronic acid is frequently employed as a coupling partner in Suzuki-Miyaura reactions, a cornerstone of modern synthetic organic chemistry for C-C bond formation.

Copper(I)-Mediated Cyanation

This compound can participate in copper(I)-catalyzed cyanation reactions, enabling the introduction of nitrile functionalities onto aromatic systems.

Synthesis of Biologically Active Compounds

Its unique structure makes it a useful intermediate for the construction of molecules with potential biological and pharmacological activities, facilitating drug discovery efforts.

02 /Properties

Molecular weight	179.97
Linear formula	HCOC6H3(OCH3)B(OH)2
Application	Reactant for:• Copper(I)-mediated cyanation1• Suzuki-Miyaura cross-coupling reactions2• Preparation of biologically and pharmacologically active molecules3
Melting point	214-217 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3261 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34
Safety statements (S)	22-26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

121124-97-8

MDL number

MFCD02093661

PubChem substance

24873659

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-Formyl-4-methoxyphenylboronic acid used for?

3-Formyl-4-methoxyphenylboronic acid is primarily used as a reactant in copper(I)-mediated cyanation, Suzuki-Miyaura cross-coupling reactions, and for the preparation of biologically and pharmacologically active molecules.

What is the CAS number and formula for 3-Formyl-4-methoxyphenylboronic acid?

The CAS number is 121124-97-8, and the linear formula is HCOC6H3(OCH3)B(OH)2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical for research and development purposes. The exact purity and grade are specified on the product's Certificate of Analysis. TSS does not represent this product as USP, EP, BP, or pharmacopoeia grade.

How should 3-Formyl-4-methoxyphenylboronic acid be handled safely?

This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection, must be used. Consult the Safety Data Sheet for detailed handling instructions.

How is 3-Formyl-4-methoxyphenylboronic acid shipped and exported?

3-Formyl-4-methoxyphenylboronic acid is shipped as a hazardous material, UN 3261, Class 8, Packing Group II. Tech Serve Solutions is an experienced global exporter of fine chemicals.