2-Coumaranone
2-Coumaranone (CAS: 553-86-6, C8H6O2) is a valuable organic compound with a molecular weight of 134.13 g/mol. This benzofuran derivative serves as a key building block in chemical synthesis and has been utilised in biochemical research. Its applications include studies on the effects of coumarins in biological systems and as a probe for enzyme activity.
Biochemical Research
2-Coumaranone has been employed in research to investigate the impact of coumarins on induced neoplasia in animal models, specifically focusing on rat mammary gland development.
Enzyme Activity Probe
This compound serves as a useful probe for the detection and study of specific enzyme activities that are responsible for hydrolysing 2-hydroxybenzofuran structures.
Chemical Synthesis
As a heterocyclic building block, 2-Coumaranone is utilised in the synthesis of more complex organic molecules and pharmaceutical intermediates.
| Molecular weight | 134.13 |
|---|---|
| Empirical formula | C8H6O2 |
| Assay | 97% |
| Boiling point | 248-250 °C(lit.) |
| Solubility | H2O: soluble3.8 g/L at 30 °C |
| Application | 2-Coumaranone has been used to study the effects of coumarins on 7,12-dimethyibenz(a)anthracene induced neoplasia of the rat mammary gland1. It was employed as probe for detecting enzymes which hydrolyze 2-hydroxybenzofuran structures2. |
| Melting point | 49-51 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 125 °C / 257 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CYP1A2(1544) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Coumaranone used for?
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2-Coumaranone is used in biochemical research, as a probe for detecting enzymes that hydrolyse 2-hydroxybenzofuran structures, and as a building block in chemical synthesis.
What are the CAS number and chemical formula for 2-Coumaranone?
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The CAS number for 2-Coumaranone is 553-86-6 and its chemical formula is C8H6O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Coumaranone with a purity of 97% (Assay). We do not represent this product as USP, BP, or EP grade.
How should 2-Coumaranone be handled safely?
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2-Coumaranone is a Warning substance. It causes skin irritation (H315), may cause an allergic skin reaction (H317), and causes serious eye irritation (H319). Recommended personal protective equipment includes eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. Always refer to the Safety Data Sheet before handling.
Is 2-Coumaranone available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Coumaranone.
How can I request a sample or quote for 2-Coumaranone?
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To request a sample or a quote for 2-Coumaranone, please contact our sales team through the website or by phone.
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