ABT-491 hydrochloride
ABT-491 hydrochloride (CAS: 189689-94-9), a research chemical with the formula C28H22N5O2F · HCl and a molecular weight of 515.97 g/mol, is supplied by TSS. This compound is identified as a bioactive small molecule relevant to cell signaling and neuroscience research. It is primarily utilized in laboratory settings for scientific investigation into complex biological pathways and as a potential therapeutic candidate.
- IUPAC
- 4-Ethynyl-N,N-dimethyl-3-[3-fluoro-4-[(2-methyl-1H-imidazo-[4,5-c]pyridin-1-yl)methyl]benzoyl]-1H-indole-1-carboxamide hydrochloride,A-137491

Cell Signaling Research
ABT-491 hydrochloride serves as a valuable tool for researchers investigating cell signaling pathways. Its application aids in understanding the intricate mechanisms governing cellular communication and responses in various biological contexts.
Neuroscience Investigations
This compound is employed in neuroscience research to explore neuronal function and pathways. It can assist in elucidating the molecular underpinnings of neurological processes and potential therapeutic targets.
Drug Discovery and Development
As an approved therapeutic candidate, ABT-491 hydrochloride is studied for its potential pharmaceutical applications. It is used in preclinical research to evaluate efficacy and safety profiles for future drug development.
Lipid Signaling Studies
The compound finds application in studies focusing on lipids in cell signaling. Researchers utilise it to investigate the role of specific lipid mediators in cellular processes and disease states.
| Molecular weight | 515.97 |
|---|---|
| Empirical formula | C28H22N5O2F · HCl |
| Assay | ≥98% (HPLC) |
| Colour | white to beige |
| Solubility | H2O: freely soluble22 mg/mL |
| Storage temperature | 2-8°C |
| Melting point | 170-178 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is ABT-491 hydrochloride used for?
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ABT-491 hydrochloride is a research chemical used in the investigation of cell signaling, neuroscience, and as a potential therapeutic candidate. It is particularly relevant for studies involving lipids in cell signaling and platelet activating factors.
What are the CAS number and formula for ABT-491 hydrochloride?
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The CAS number for ABT-491 hydrochloride is 189689-94-9, and its chemical formula is C28H22N5O2F · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies ABT-491 hydrochloride with an assay of ≥98% (HPLC). This is a research-grade chemical, and TSS does not represent it as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for ABT-491 hydrochloride?
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Handling ABT-491 hydrochloride requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It has a WGK Germany rating of 3, indicating a high hazard level.
How is ABT-491 hydrochloride shipped and exported?
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ABT-491 hydrochloride is typically stored at 2-8°C and is available for global export by Tech Serve Solutions. Packaging and shipping adhere to international regulations for chemical substances.
How can I request a quote or sample of ABT-491 hydrochloride?
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To request a quote or a sample of ABT-491 hydrochloride, please contact the Tech Serve Solutions sales team through our website or direct contact information.
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