R(+)-SCH-23390 hydrochloride
R(+)-SCH-23390 hydrochloride (CAS: 125941-87-9) is a potent and selective antagonist of the dopamine D1 receptor. This research chemical, with a molecular weight of 324.24 g/mol and empirical formula C17H18ClNO · HCl, is supplied as a white solid. It is primarily utilised in neuroscience research to investigate dopaminergic pathways and neurotransmission. Its applications extend to cell biology and signaling studies.
- IUPAC
- R(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride

Dopamine D1 Receptor Antagonist
R(+)-SCH-23390 hydrochloride is a highly selective antagonist for the dopamine D1 receptor, making it an indispensable tool for studying dopaminergic neurotransmission and its role in various physiological and pathological processes.
Neuroscience Research
This compound is widely used in preclinical neuroscience research to probe the functions of the D1 receptor in areas such as learning, memory, motivation, and motor control. It aids in understanding conditions influenced by dopamine signaling.
Cell Signaling Studies
Researchers employ R(+)-SCH-23390 hydrochloride to investigate signal transduction pathways downstream of the D1 receptor, contributing to a deeper understanding of cellular responses to dopaminergic stimuli.
Bioactive Molecule Research
As a well-characterised bioactive small molecule, it serves as a reference compound in drug discovery and pharmacological research focused on dopaminergic systems.
| Molecular weight | 324.24 |
|---|---|
| Empirical formula | C17H18ClNO · HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | H2O: >5 mg/mL |
| Optical activity | [α]/D +32.1°, c = 1 in DMF(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... DRD1(1812) |
|---|---|
| Storage Condition | protect from light |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is R(+)-SCH-23390 hydrochloride used for?
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R(+)-SCH-23390 hydrochloride is primarily used as a selective antagonist of the dopamine D1 receptor in neuroscience and cell biology research to investigate dopaminergic pathways and neurotransmission.
What is the CAS number and molecular formula for R(+)-SCH-23390 hydrochloride?
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The CAS number for R(+)-SCH-23390 hydrochloride is 125941-87-9, and its empirical formula is C17H18ClNO · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies R(+)-SCH-23390 hydrochloride with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should R(+)-SCH-23390 hydrochloride be handled?
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Handling R(+)-SCH-23390 hydrochloride requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It should be protected from light during storage.
Is R(+)-SCH-23390 hydrochloride a controlled substance?
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The provided data does not indicate that R(+)-SCH-23390 hydrochloride is a controlled substance.
How is R(+)-SCH-23390 hydrochloride packed, shipped, and exported?
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R(+)-SCH-23390 hydrochloride is supplied as a white solid and is carefully packed to ensure stability during shipping and export globally by Tech Serve Solutions.
How can I request a sample or quote for R(+)-SCH-23390 hydrochloride?
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To request a sample or quote for R(+)-SCH-23390 hydrochloride, please contact Tech Serve Solutions directly through our website or sales representatives.
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