R(+)-Baclofen hydrochloride
R(+)-Baclofen hydrochloride (CAS: 63701-55-3) is a white solid compound with a molecular weight of 250.12 g/mol and empirical formula C10H12ClNO2·HCl. This chiral molecule acts as a GABAergic agent, primarily functioning as a selective agonist for GABA-B receptors. It is widely utilised in neuroscience research for studying neurotransmission and neuronal signalling.
- IUPAC
- Arbaclofen hydrochloride,R(+)-β-(Aminomethyl)-4-chlorobenzenepropanoic acid hydrochloride,STX209
- Synonyms
- Arbaclofen hydrochlorideR(+)-β-(Aminomethyl)-4-chlorobenzenepropanoic acid hydrochlorideSTX209
Neuroscience Research
R(+)-Baclofen hydrochloride serves as a valuable tool in neuroscience research for investigating the role of GABA-B receptors in synaptic transmission and neuronal excitability. Its selective agonism allows researchers to probe specific cellular pathways.
Cell Signaling Studies
As a bioactive small molecule, this compound is employed in studies focused on cell signaling mechanisms, particularly those involving the gamma-aminobutyric acid (GABA) pathway. It helps elucidate the downstream effects of GABA-B receptor activation.
Pharmacological Tool
The compound is used as a pharmacological agent to understand the complex interplay of neurotransmitters in the central nervous system. Its specific action on GABA-B receptors makes it useful for differentiating receptor subtype functions.
| Molecular weight | 250.12 |
|---|---|
| Empirical formula | C10H12ClNO2 · HCl |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >20 mg/mLH2O: soluble26 mg/mL (Solutions may be stored for several weeks at 4 °C.) |
| Optical activity | [α]28/D +3.8°, c = 0.9 in methanol(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... GABBR1(2550)mouse ... GABBR1(54393)rat ... GABBR1(81657) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is R(+)-Baclofen hydrochloride used for?
+
R(+)-Baclofen hydrochloride is primarily used in neuroscience research as a selective GABA-B receptor agonist to study neurotransmission, cell signaling, and neuronal excitability.
What is the CAS number and formula for R(+)-Baclofen hydrochloride?
+
The CAS number is 63701-55-3 and the empirical formula is C10H12ClNO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies R(+)-Baclofen hydrochloride as a technical/research grade chemical. We do not represent it as USP, BP, EP, or pharmacopoeia grade.
How should R(+)-Baclofen hydrochloride be handled?
+
Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a WGK Germany rating of 3, indicating it is hazardous to water.
Is R(+)-Baclofen hydrochloride a controlled substance?
+
The provided data does not indicate that R(+)-Baclofen hydrochloride is a controlled substance.
How is R(+)-Baclofen hydrochloride packed, shipped, and exported?
+
R(+)-Baclofen hydrochloride is carefully packed to ensure stability during transit. Tech Serve Solutions exports globally, adhering to all relevant shipping regulations for chemical compounds.
How can I request a sample or quote for R(+)-Baclofen hydrochloride?
+
Please contact our sales department directly through our website or by phone to request a sample or a detailed quotation for R(+)-Baclofen hydrochloride.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis