1,1′-Bis[(2R,5R)-2,5-dimethylphospholano]ferrocene

CAS 540475-45-45R)-2Chemical Synthesis

1,1′-Bis[(2R,5R)-2,5-dimethylphospholano]ferrocene (CAS: 540475-45-4) is a chiral ferrocene-based diphosphine ligand with the molecular formula C22H32FeP2 and a molecular weight of 414.28 g/mol. It belongs to the highly effective DuPhos/BPE class of privileged ligands. This compound is primarily utilised in asymmetric synthesis to catalyse enantioselective reactions, enabling the production of chiral molecules with high stereochemical control.

IUPAC: R,R-Me-Ferrocelane™
Synonyms: 1,1′-Bis[(2R,5R)-2,5-dimethylphospholano]ferrocene

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1,1′-Bis[(2R,5R)-2,5-dimethylphospholano]ferrocene (5R)-2) — chemical structure, CAS 540475-45-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral CatalystsLigandsand ReagentsDuPhos/BPE

01 /Applications

Asymmetric Catalysis

Serves as a crucial chiral ligand in transition metal-catalysed asymmetric reactions, facilitating the synthesis of enantiomerically enriched compounds. Its structure is optimised for high selectivity and catalytic activity.

Homogeneous Catalysis

Employed in various homogeneous catalytic processes, particularly where stereochemical control is paramount. It acts as a directing ligand, influencing the stereochemical outcome of the reaction.

Chiral Ligand Development

Represents a key example within the DuPhos/BPE family, valuable for researchers developing novel catalytic systems for fine chemical and pharmaceutical synthesis.

02 /Properties

Molecular weight	414.28
Empirical formula	C22H32FeP2
Assay	≥97%
Application	DuPhos and BPE Ligands: Highly Efficient Privileged Ligands
Melting point	99.9-101.5 °C

03 /Identifiers & registry

CAS number

540475-45-4

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is 1,1′-Bis[(2R,5R)-2,5-dimethylphospholano]ferrocene used for?

This compound is a privileged chiral ligand primarily used in asymmetric synthesis to catalyse enantioselective reactions, leading to the production of chiral molecules with high stereochemical control.

What is the CAS number and formula for 1,1′-Bis[(2R,5R)-2,5-dimethylphospholano]ferrocene?

The CAS number is 540475-45-4 and the empirical formula is C22H32FeP2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical with an assay of ≥97%. It is not represented as USP, BP, EP, or other pharmacopoeial grades.

What are the safety and handling considerations for this compound?

According to GHS classifications, this compound may cause skin irritation and serious eye irritation. Handle with appropriate personal protective equipment in a well-ventilated area.