1,1′-Bis[(2R,5R)-2,5-diethylphospholano]ferrocene

CAS 147762-89-85R)-2Chemical Synthesis

1,1′-Bis[(2R,5R)-2,5-diethylphospholano]ferrocene (CAS: 147762-89-8) is a chiral ferrocenyl diphosphine ligand with the molecular formula C26H40FeP2 and a molecular weight of 470.39 g/mol. This compound is a key component in asymmetric synthesis, particularly recognised for its utility in catalysing stereoselective reactions. It is often employed in the development of enantiomerically pure compounds, contributing to advancements in pharmaceutical and fine chemical manufacturing.

IUPAC: R,R-Et-Ferrocelane™
Synonyms: 1,1′-Bis[(2R,5R)-2,5-diethylphospholano]ferrocene(2R,5R)-2,5-diethylphospholano]ferrocene147762-89-8C26H40FeP2R,R-Et-Ferrocelane™

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1,1′-Bis[(2R,5R)-2,5-diethylphospholano]ferrocene (5R)-2) — chemical structure, CAS 147762-89-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral CatalystsLigandsand ReagentsDuPhos/BPE

01 /Applications

Asymmetric Catalysis

This ferrocene-based diphosphine ligand is widely used in homogeneous asymmetric catalysis to promote high enantioselectivity in various transformations. Its chiral structure enables the synthesis of specific enantiomers with high optical purity.

Hydrogenation Reactions

It serves as an effective ligand in metal-catalysed hydrogenation processes, facilitating the stereoselective reduction of prochiral substrates to chiral products.

Pharmaceutical Intermediate Synthesis

The ability to control stereochemistry makes this compound invaluable in the synthesis of chiral pharmaceutical intermediates, where precise molecular architecture is critical for drug efficacy.

Ligand for Metal Complexes

It functions as a privileged ligand, forming stable complexes with transition metals, which are then employed as catalysts in a range of organic synthesis applications.

02 /Properties

Molecular weight	470.39
Empirical formula	C26H40FeP2
Optical activity	[α]20/D +380°, c = 1 in chloroform
Application	DuPhos and BPE Ligands: Highly Efficient Privileged Ligands
Melting point	85-91 °C

03 /Identifiers & registry

CAS number

147762-89-8

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is 1,1′-Bis[(2R,5R)-2,5-diethylphospholano]ferrocene used for?

1,1′-Bis[(2R,5R)-2,5-diethylphospholano]ferrocene is primarily used as a chiral ligand in asymmetric synthesis and catalysis, enabling the stereoselective production of enantiomerically pure compounds.

What is the CAS number and formula for this compound?

The CAS number is 147762-89-8 and the empirical formula is C26H40FeP2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical with a specified optical activity of [α]20/D +380°, c = 1 in chloroform. We do not represent this product as USP, BP, or EP grade.

How should 1,1′-Bis[(2R,5R)-2,5-diethylphospholano]ferrocene be handled?

This compound is classified under WGK Germany 3, indicating it is hazardous. Handle with appropriate personal protective equipment in a well-ventilated area. Avoid contact with skin and eyes. Refer to the Safety Data Sheet (SDS) for detailed handling and safety information.

Is this product available for export?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents, including 1,1′-Bis[(2R,5R)-2,5-diethylphospholano]ferrocene.

How can I request a quote or sample?

To request a quote or sample of 1,1′-Bis[(2R,5R)-2,5-diethylphospholano]ferrocene, please contact our sales department through the website or by phone.