(S)-Boc-5-oxopyrrolidine-2-carboxylic acid
(S)-Boc-5-oxopyrrolidine-2-carboxylic acid (CAS: 53100-44-0, C10H15NO5) is a chiral building block for asymmetric synthesis. This derivative of pyroglutamic acid, protected with a Boc group, serves as a valuable intermediate in complex chemical syntheses. It is particularly useful in peptide chemistry and the development of heterocyclic compounds. TSS supplies this compound with a minimum assay of 97%, maintaining strict quality control for research and development applications.
- IUPAC
- (−)-1-Boc-L-pyroglutamic acid,Boc-pyr-OH

Asymmetric Synthesis
This chiral molecule is a key intermediate in the synthesis of enantiomerically pure compounds, enabling stereoselective transformations in organic chemistry.
Peptide Chemistry
As a protected pyroglutamic acid derivative, it is employed in the synthesis of peptides and peptidomimetics, facilitating the construction of complex biomolecules.
Heterocyclic Compound Synthesis
Its pyrrolidine ring structure makes it a useful precursor for constructing various heterocyclic scaffolds important in medicinal chemistry.
Chemical Biology Research
Used as a building block in the design and synthesis of novel biologically active molecules for probing cellular pathways and drug discovery.
| Molecular weight | 229.23 |
|---|---|
| Empirical formula | C10H15NO5 |
| Assay | 97% |
| Optical activity | [α]22/D −35.0, c = 1 in chloroform |
| Storage temperature | 2-8°C |
| Melting point | 118-123 °C (dec.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-Boc-5-oxopyrrolidine-2-carboxylic acid used for?
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(S)-Boc-5-oxopyrrolidine-2-carboxylic acid is primarily used as a chiral building block in asymmetric synthesis, peptide chemistry, and the synthesis of heterocyclic compounds. It is valuable in chemical biology research for creating novel molecules.
What is the CAS number and molecular formula?
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The CAS number for (S)-Boc-5-oxopyrrolidine-2-carboxylic acid is 53100-44-0 and its molecular formula is C10H15NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-Boc-5-oxopyrrolidine-2-carboxylic acid with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations?
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This compound is a skin, eye, and respiratory irritant. Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation. Store at 2-8°C.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, and (S)-Boc-5-oxopyrrolidine-2-carboxylic acid can be packed and shipped internationally.
How can I request a quote or sample?
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To request a quote or a sample of (S)-Boc-5-oxopyrrolidine-2-carboxylic acid, please contact our sales team through the website or by phone.
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