2-Amino-3,4,5,6-tetrafluorobenzoic acid
2-Amino-3,4,5,6-tetrafluorobenzoic acid (CAS: 1765-42-0), a fluorinated aromatic amino acid derivative with the molecular formula H₂NC₆F₄CO₂H and a molecular weight of 209.10, is a valuable building block in chemical synthesis. It is primarily utilised in the development of novel organic compounds, peptide chemistry, and as an intermediate in the synthesis of complex molecules within chemical biology research. Its unique tetrafluorinated structure offers distinct reactivity and properties for advanced chemical applications.
- IUPAC
- 3,4,5,6-Tetrafluoroanthranilic acid
- Synonyms
- 3,4,5,6-Tetrafluoroanthranilic acid6-tetrafluorobenzoic acidH2NC6F4CO2H

Chemical Synthesis Intermediate
This compound serves as a key intermediate in the synthesis of complex organic molecules. Its tetrafluorinated aromatic ring provides unique electronic properties for further chemical modifications and the introduction of fluorine atoms into target structures.
Peptide and Unnatural Amino Acid Chemistry
As an unnatural amino acid derivative, it is employed in the design and synthesis of modified peptides. Incorporating this fluorinated moiety can alter peptide conformation, stability, and biological activity, finding applications in medicinal chemistry and drug discovery.
Research and Development
2-Amino-3,4,5,6-tetrafluorobenzoic acid is a critical reagent in academic and industrial research laboratories exploring novel chemical entities. Its specific structure supports advancements in areas like chemical biology and materials science.
| Molecular weight | 209.10 |
|---|---|
| Linear formula | H2NC6F4CO2H |
| Assay | 98% |
| Melting point | 141-143 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-3,4,5,6-tetrafluorobenzoic acid used for?
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2-Amino-3,4,5,6-tetrafluorobenzoic acid is primarily used as a building block in chemical synthesis, particularly in the fields of peptide chemistry, chemical biology, and the development of unnatural amino acid derivatives for research purposes.
What is the CAS number and molecular formula for this product?
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The CAS number is 1765-42-0, and the molecular formula is H₂NC₆F₄CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-3,4,5,6-tetrafluorobenzoic acid with a purity of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety precautions when handling this chemical?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). When handling, it is recommended to use a dust mask type N95 (US), wear Eyeshields, and Gloves. Ensure adequate ventilation and avoid breathing dust.
How is 2-Amino-3,4,5,6-tetrafluorobenzoic acid packed, shipped, and exported?
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Tech Serve Solutions ensures all chemicals are carefully packed in compliance with international shipping regulations. We export globally to qualified research and industrial facilities.
How can I request a sample or a quote for 2-Amino-3,4,5,6-tetrafluorobenzoic acid?
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To request a sample or a quote, please visit the product page on our website and use the 'Request Sample' or 'Enquire Now' buttons, providing your contact details and specific requirements.
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