1,1′-Bis[(2S,5S)-2,5-dimethylphospholano]ferrocene
1,1′-Bis[(2S,5S)-2,5-dimethylphospholano]ferrocene (CAS 162412-87-5) is a chiral ferrocene-based ligand with the molecular formula C22H32FeP2 and a molecular weight of 414.28 g/mol. It belongs to the class of privileged ligands, specifically the DuPhos/BPE family. This compound is a key chiral auxiliary and catalyst component used extensively in asymmetric synthesis to achieve high enantioselectivity in various chemical transformations.
- IUPAC
- S,S-Me-Ferrocelane™
- Synonyms
- 1,1′-Bis[(2S,5S)-2,5-dimethylphospholano]ferrocene(S,S)-Me-Ferrocelane™
![1,1′-Bis[(2S,5S)-2,5-dimethylphospholano]ferrocene (5S)-2) — chemical structure, CAS 162412-87-5; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162412-87-5.png&w=3840&q=75)
Asymmetric Catalysis
This ferrocene-derived phospholane ligand is employed as a crucial component in transition metal-catalyzed asymmetric reactions. It facilitates the synthesis of enantiomerically enriched compounds, vital for pharmaceutical and fine chemical production.
Chiral Ligand in Synthesis
As a privileged chiral ligand, it plays a significant role in promoting stereoselective transformations. Its specific structure enables precise control over reaction pathways, leading to desired stereoisomers.
Precursor for Catalytic Systems
It serves as a building block for preparing highly active and enantioselective homogeneous catalysts. These catalytic systems are instrumental in various organic synthesis applications where chirality is paramount.
| Molecular weight | 414.28 |
|---|---|
| Empirical formula | C22H32FeP2 |
| Optical activity | [α]22/D −331°, c = 1 in chloroform-d |
| Application | DuPhos and BPE Ligands: Highly Efficient Privileged Ligands |
| Melting point | 88.9-98.5 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,1′-Bis[(2S,5S)-2,5-dimethylphospholano]ferrocene used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis, facilitating the enantioselective synthesis of valuable chemical intermediates and active pharmaceutical ingredients.
What are the CAS number and molecular formula for this compound?
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The CAS number is 162412-87-5, and the molecular formula is C22H32FeP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a reported optical activity of [α]22/D −331°, c = 1 in chloroform-d. It is supplied for research and development purposes. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling considerations for this chemical?
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This compound is classified under WGK 2, indicating it is hazardous to water. Appropriate personal protective equipment, including gloves, eye protection, and protective clothing, should be used when handling. Ensure adequate ventilation.
How is this chemical packed, shipped, and exported by TSS?
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Tech Serve Solutions packages chemicals according to international shipping regulations, ensuring safe transport. As a global supplier and exporter, we handle all necessary documentation for seamless international delivery.
How can I request a quote or sample for 1,1′-Bis[(2S,5S)-2,5-dimethylphospholano]ferrocene?
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Please contact our sales team directly via the website or by phone to request a quotation or a sample of this product.
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