AC-41848 hydrate
AC-41848 hydrate (CAS: 400856-69-1) is a potent, cell-permeable, and subtype-selective agonist for the retinoic acid receptor RARγ. With a molecular weight of 452.21 g/mol (anhydrous basis) and the empirical formula C21H21BrCl2N2 · xH2O, this compound is supplied as a solid with an assay of ≥98% by HPLC. It finds application in research areas such as cell biology, cell signaling, and gene regulation, particularly within studies involving nuclear receptors.
- IUPAC
- 1-[(2,4-Dichlorophenyl)methyl]-6,7,8,9-tetrahydro-3-phenyl-5H-imidazo[1,2-a]azepinium bromide hydrate
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Research in Cell Biology
AC-41848 hydrate serves as a valuable tool for researchers investigating cellular processes. Its specific activity as an RARγ agonist aids in studying gene expression and cellular differentiation regulated by retinoic acid pathways.
Investigating Cell Signaling Pathways
As a selective agonist, this compound is employed to elucidate the intricate mechanisms of cell signaling. It is particularly useful in understanding the roles of RARγ in pathways related to cell communication and response.
Neuroscience Research Applications
This molecule can be utilised in neuroscience research to explore the influence of retinoic acid receptors on neuronal function and development. Its subtype selectivity allows for focused investigation within this complex field.
Gene Regulation and Expression Studies
AC-41848 hydrate is instrumental in studying the regulation of gene expression. Researchers use it to understand how RARγ activation impacts transcriptional control and related biological processes.
| Molecular weight | 452.21 (anhydrous basis) |
|---|---|
| Empirical formula | C21H21BrCl2N2 · xH2O |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Solubility | DMSO: ~14 mg/mLH2O: >5 mg/mL |
| Storage temperature | 2-8°C |
| Application | AC-41848 is a potent, cell permeable, and subtype selective retinoic acid receptor RARγ agonist. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccatedunder inert gas |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is AC-41848 hydrate used for?
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AC-41848 hydrate is used as a potent, cell-permeable, and subtype-selective retinoic acid receptor RARγ agonist in research applications, particularly in cell biology, cell signaling, neuroscience, and gene regulation studies.
What is the CAS number and formula for AC-41848 hydrate?
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The CAS number for the anhydrous form is 400856-69-1. The empirical formula is C21H21BrCl2N2 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies AC-41848 hydrate with a minimum purity of ≥98% as determined by HPLC. This is a research-grade chemical and not intended for human or animal use, nor is it represented as USP, BP, EP, or pharmaceutical grade.
How should AC-41848 hydrate be handled and stored safely?
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AC-41848 hydrate is a Warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves. Store desiccated under an inert gas at 2-8°C.
How is this chemical packed, shipped, and exported?
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AC-41848 hydrate is typically supplied as a solid. As a global supplier, Tech Serve Solutions handles all aspects of packing, shipping, and exporting according to international regulations.
How can I request a sample or quote for AC-41848 hydrate?
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To request a sample or a quotation for AC-41848 hydrate, please contact our sales department through the website or by direct inquiry, providing your specific requirements.
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