ABT-751 hydrochloride
ABT-751 hydrochloride (CAS: 141450-48-8), with the molecular formula C18H17N3O4S · HCl and a molecular weight of 407.87 g/mol, is a pink to purple powder. This compound serves as a valuable research chemical, primarily recognised for its role as a microtubule inhibitor. It finds application in studies related to cell biology, cell signaling, and neuroscience, offering insights into cytoskeletal dynamics and related cellular processes.
- IUPAC
- N-[2-[(4-Hydroxyphenyl)amino]-3-pyridyl]-4-methoxybenzenesulfonamide hydrochloride

Microtubule Inhibition Studies
ABT-751 hydrochloride acts as an inhibitor of microtubule polymerization. This makes it a useful tool for researchers investigating the role of microtubules in cellular processes such as cell division, intracellular transport, and cell shape maintenance.
Cell Biology Research
As a bioactive small molecule, ABT-751 hydrochloride is employed in cell biology research to probe cellular mechanisms. Its effects on the cytoskeleton and cell signaling pathways can provide valuable data for understanding complex biological systems.
Drug Discovery and Development
Identified as an approved therapeutic/drug candidate, ABT-751 hydrochloride is of interest in drug discovery. Its specific mechanisms of action may inform the development of novel therapeutic agents targeting diseases where microtubule function is critical.
| Molecular weight | 407.87 |
|---|---|
| Empirical formula | C18H17N3O4S · HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | pink to purple |
| Solubility | DMSO: ≥15 mg/mL |
| Storage temperature | 2-8°C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is ABT-751 hydrochloride used for?
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ABT-751 hydrochloride is primarily used as a research chemical, notably as a microtubule inhibitor, and in studies related to cell biology, cell signaling, and neuroscience. It is also recognized as an approved therapeutic/drug candidate.
What is the CAS number and molecular formula for ABT-751 hydrochloride?
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The CAS number for ABT-751 hydrochloride is 141450-48-8, and its molecular formula is C18H17N3O4S · HCl.
What grade and purity does Tech Serve Solutions supply for ABT-751 hydrochloride?
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Tech Serve Solutions supplies ABT-751 hydrochloride with a purity of ≥98% (HPLC). We do not represent this product as meeting any pharmacopoeial standards such as USP, BP, or EP unless explicitly stated in the product data.
How should ABT-751 hydrochloride be handled?
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ABT-751 hydrochloride is classified as a Warning substance. It is harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation (H302, H315, H319, H335). Handle with appropriate personal protective equipment in a well-ventilated area, and avoid contact with skin, eyes, and clothing. Refer to the Safety Data Sheet for detailed handling information.
How is ABT-751 hydrochloride packed, shipped, and exported?
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ABT-751 hydrochloride is typically supplied as a powder and stored at 2-8°C. Tech Serve Solutions, as a specialist global supplier and exporter, handles its packaging, shipping, and export in compliance with all relevant regulations for chemical products.
How can I request a quote or sample for ABT-751 hydrochloride?
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To request a quote or sample for ABT-751 hydrochloride, please contact our sales team through the TSS website or by phone. Our experts will assist you with your inquiry.
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