4-Nitrothiophenol
4-Nitrothiophenol (CAS: 1849-36-1, Formula: O2NC6H4SH, MW: 155.17) is a key organic building block and sulfur compound. This nitro-substituted aromatic thiol, typically supplied at 80% purity, serves as a versatile intermediate in chemical synthesis. It is particularly useful in the preparation of various organic molecules and functional materials, playing a crucial role in research and development laboratories.
- IUPAC
- 4-Nitrobenzenethiol
- Synonyms
- 4-Nitrobenzenethiol

Organic Synthesis Intermediate
4-Nitrothiophenol is employed as a crucial building block in the synthesis of complex organic molecules. Its reactive thiol group and nitro-substituted aromatic ring allow for diverse chemical transformations, facilitating the creation of novel compounds for research.
Pharmaceutical Research
This compound can be utilised in the development of potential pharmaceutical agents. Its structure lends itself to incorporation into molecules designed for biological activity, supporting early-stage drug discovery efforts.
Material Science
The unique electronic properties imparted by the nitro and thiol groups make 4-Nitrothiophenol a candidate for use in the creation of functional materials. It can be incorporated into polymers or self-assembled monolayers for specific applications.
| Molecular weight | 155.17 |
|---|---|
| Linear formula | O2NC6H4SH |
| Assay | 80% |
| Storage temperature | 2-8°C |
| Melting point | 72-77 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Nitrothiophenol used for?
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4-Nitrothiophenol is primarily used as an intermediate in organic synthesis, for research in pharmaceutical development, and in material science applications.
What are the CAS number and formula for 4-Nitrothiophenol?
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The CAS number for 4-Nitrothiophenol is 1849-36-1, and its formula is O2NC6H4SH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Nitrothiophenol with an assay of 80%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should 4-Nitrothiophenol be handled safely?
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Handle 4-Nitrothiophenol with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure good ventilation, as it can cause skin, eye, and respiratory irritation (H315, H319, H335).
Is 4-Nitrothiophenol a controlled substance?
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The provided data does not indicate that 4-Nitrothiophenol is a controlled substance.
How is 4-Nitrothiophenol packed and exported?
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4-Nitrothiophenol is stored at 2-8°C. As a global supplier, Tech Serve Solutions offers export services for this chemical, adhering to all relevant shipping regulations.
How can I request a sample or quote for 4-Nitrothiophenol?
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To request a sample or a quote for 4-Nitrothiophenol, please contact our sales team through the website or by phone.
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