AA-861

CAS 80809-81-0C21H26O3Biochemicals & Reagents

AA-861 (CAS: 80809-81-0), with the molecular formula C21H26O3 and a molecular weight of 326.43 g/mol, is a bioactive small molecule. It is known to be an inhibitor within the arachidonic acid cascade, specifically interacting with lipoxygenases. This compound is utilized in biochemical research for studying cell signaling pathways, particularly those involving lipids and inflammation. Its precise role in enzymatic processes makes it a valuable reagent for scientists investigating these complex biological mechanisms.

IUPAC: 2-(12-Hydroxydodeca-5,10-diynyl)-3,5,6-trimethyl-p-benzoquinone

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AA-861 (C21H26O3) — chemical structure, CAS 80809-81-0; Life Science, fine chemical supplied by Tech Serve Solutions

A-AMArachidonic Acid CascadeBioactive Small MoleculesBiochemicals and ReagentsCell BiologyEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymesInhibitorsand Substrates

01 /Applications

Research into Arachidonic Acid Cascade

AA-861 serves as a valuable tool for researchers investigating the arachidonic acid cascade. Its inhibitory properties against lipoxygenases allow for detailed studies into the downstream effects of this critical biochemical pathway.

Cell Signaling and Neuroscience Studies

This compound is used in the study of lipid signaling pathways within cells. Its interaction with enzymes like lipoxygenase makes it relevant for research in cell biology and neuroscience, particularly in understanding inflammatory responses.

Enzyme Inhibition Research

As a known inhibitor of lipoxygenase, AA-861 is employed in biochemical laboratories to understand enzyme mechanisms. It helps in elucidating the specific roles and inhibition profiles of enzymes within metabolic pathways.

02 /Properties

Molecular weight	326.43
Empirical formula	C21H26O3
Assay	≥98% (HPLC)
Solubility	ethanol: soluble
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

80809-81-0

MDL number

MFCD00210243

PubChem substance

24278214

05 /Additional specifications

Gene Information	human ... ALOX5(240)rat ... Alox5(25290)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is AA-861 used for?

AA-861 is primarily used in biochemical research as an inhibitor of lipoxygenase enzymes, contributing to the study of the arachidonic acid cascade and lipid signaling pathways.

What are the CAS number and formula for AA-861?

The CAS number for AA-861 is 80809-81-0, and its molecular formula is C21H26O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies AA-861 with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should AA-861 be handled safely?

AA-861 is classified with GHS07 and a Warning signal word. It can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.