A-331440 dihydrochloride
A-331440 dihydrochloride (CAS: 392338-13-5) is a white to off-white solid with the molecular formula C22H27N3O · 2HCl. This compound is primarily utilised as a research chemical, specifically within cell biology and neuroscience studies. It functions as a potent antagonist, particularly targeting specific GPCRs. Its high purity (≥98% HPLC) makes it suitable for demanding in vitro research applications in pharmacology and biochemistry.
- IUPAC
- 4’-[3-[(3(R)-Dimethylamino-1-pyrrolidinyl]propoxy]-[1,1-biphenyl]-4‘-carbonitrile dihydrochloride
.png&w=3840&q=75)
Pharmacological Research
A-331440 dihydrochloride serves as a valuable tool for investigating G protein-coupled receptors (GPCRs). Its antagonist properties are crucial for probing receptor function and signalling pathways in various biological systems.
Neuroscience Studies
This compound is employed in research focused on the central nervous system, where it can help elucidate the roles of specific neurotransmitter systems and their associated receptors. Its application aids in understanding neurological processes.
Cell Signaling Investigations
As a modulator of cell signalling pathways, A-331440 dihydrochloride is used to study cellular responses and signal transduction mechanisms. Its precise action allows researchers to dissect complex biological interactions.
| Molecular weight | 422.39 |
|---|---|
| Empirical formula | C22H27N3O · 2HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | H2O: ≥10 mg/mL |
| Storage temperature | 2-8°C |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is A-331440 dihydrochloride used for?
+
A-331440 dihydrochloride is primarily used as a research chemical for pharmacological studies, particularly in neuroscience and cell signaling, where it acts as an antagonist for specific GPCRs.
What are the CAS number and molecular formula for A-331440 dihydrochloride?
+
The CAS number for the free base is 392338-13-5, and the molecular formula for the dihydrochloride salt is C22H27N3O · 2HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies A-331440 dihydrochloride with a purity of ≥98% as determined by HPLC. This compound is supplied for research purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should A-331440 dihydrochloride be handled and stored?
+
A-331440 dihydrochloride is a warning substance (GHS07) that causes serious eye irritation (H319). Handle with care using eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store refrigerated at 2-8°C in a desiccated state.
Is A-331440 dihydrochloride a controlled substance?
+
The provided data does not indicate that A-331440 dihydrochloride is a controlled substance.
How are A-331440 dihydrochloride products packed, shipped, and exported?
+
Products are carefully packed and exported by Tech Serve Solutions, adhering to all relevant regulations for the safe transport of chemicals.
How can I request a sample or quote for A-331440 dihydrochloride?
+
To request a sample or quote, please contact our sales department through the website or by direct inquiry.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents

(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis