A-77636 hydrochloride hydrate
A-77636 hydrochloride hydrate (CAS: 145307-34-2) is a white to off-white solid with the empirical formula C20H27NO3 · HCl · xH2O. This compound, with a molecular weight of 365.89 g/mol (anhydrous basis), serves as a key research tool in cell biology and neuroscience. It functions as a selective dopamine D1 receptor agonist, making it valuable for studies investigating dopaminergic neurotransmission and related cellular signalling pathways.
- IUPAC
- (−)-(1R,3S)-3-Adamantyl-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyran hydrochloride hydrate
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Dopamine Receptor Agonist Research
A-77636 hydrochloride hydrate is utilised as a selective agonist for the dopamine D1 receptor. This makes it an indispensable tool for researchers studying the function and modulation of dopaminergic pathways in the central nervous system.
Neuroscience and Cell Signaling Studies
Its specific interaction with D1 receptors makes this compound valuable for investigating neurotransmission, neuronal signalling, and the cellular mechanisms underlying neurological processes.
Bioactive Molecule Research
As a bioactive small molecule, A-77636 hydrochloride hydrate is employed in biochemical research to understand the intricate pathways involved in cellular responses and receptor interactions.
| Molecular weight | 365.89 (anhydrous basis) |
|---|---|
| Empirical formula | C20H27NO3 · HCl · xH2O |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | H2O: >10 mg/mL |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... DRD1(1812) |
|---|---|
| Storage Condition | desiccatedprotect from light |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is A-77636 hydrochloride hydrate used for?
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A-77636 hydrochloride hydrate is used as a selective dopamine D1 receptor agonist in research, particularly in neuroscience and cell signalling studies to investigate dopaminergic pathways and neurotransmission.
What are the CAS number and formula for A-77636 hydrochloride hydrate?
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The CAS number for A-77636 hydrochloride hydrate is 145307-34-2 (anhydrous). The empirical formula is C20H27NO3 · HCl · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies A-77636 hydrochloride hydrate with an assay of ≥98% determined by HPLC. This product is supplied for research purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling recommendations for A-77636 hydrochloride hydrate?
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Handling A-77636 hydrochloride hydrate requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany 3, indicating a high hazard level for aquatic life.
How is A-77636 hydrochloride hydrate shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including A-77636 hydrochloride hydrate, adhering to all relevant shipping and export regulations.
How can I request a sample or quote for A-77636 hydrochloride hydrate?
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To request a sample or a quote for A-77636 hydrochloride hydrate, please contact our sales team through the website or by phone.
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