HE-NECA

CAS 141018-30-6 (anhydrous)C18H24N6O4 · xH2OCell Biology

HE-NECA (CAS: 141018-30-6) is a research chemical with the molecular formula C18H24N6O4 · xH2O. This anhydrous compound has a molecular weight of 388.42. HE-NECA is primarily recognised for its role as an agonist in the study of adenosine receptors, particularly P2 nucleotide receptors. Its applications lie within cell biology and neuroscience research, focusing on cell signaling and neurotransmission mechanisms.

IUPAC: 2-(1-Hexyn-1-yl)adenosine-5′-N-ethyluronamide,2-Hexynyl-5′-ethylcarboxamidoadenosine
Synonyms: 2-(1-Hexyn-1-yl)adenosine-5′-N-ethyluronamide2-Hexynyl-5′-ethylcarboxamidoadenosine

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HE-NECA (C18H24N6O4 · xH2O) — chemical structure, CAS 141018-30-6 (anhydrous); Life Science, fine chemical supplied by Tech Serve Solutions

AgonistsBioactive Small MoleculesCell BiologyNeuroscienceNeurotransmissionNeurotransmitters More...

01 /Applications

Adenosine Receptor Research

HE-NECA serves as a valuable tool for investigating the function and signalling pathways of adenosine receptors, including P2 nucleotide receptors. It aids researchers in understanding receptor pharmacology and ligand interactions.

Neuroscience Studies

This compound is utilised in neuroscience to explore the roles of purinergic signalling in neuronal function and neurotransmission. It helps elucidate complex cellular mechanisms within the nervous system.

Cell Signaling Investigations

HE-NECA is employed in cell biology research to study intracellular signalling cascades triggered by purinergic receptor activation. This facilitates a deeper understanding of cellular responses and regulation.

02 /Properties

Molecular weight	388.42 (anhydrous basis)
Empirical formula	C18H24N6O4 · xH2O
Assay	≥98% (HPLC)
Form	solid
Colour	white
Solubility	DMSO: >10 mg/mLH2O: insoluble
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

141018-30-6 (anhydrous)

MDL number

MFCD03095611

PubChem substance

24278473

05 /Additional specifications

Gene Information	human ... ADORA2A(135), ADORA2B(136)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is HE-NECA used for?

HE-NECA is used in research for studying adenosine receptors, P2 nucleotide receptors, cell signaling, and neuroscience, particularly in relation to neurotransmission.

What are the CAS number and formula for HE-NECA?

The CAS number for HE-NECA (anhydrous) is 141018-30-6, and its formula is C18H24N6O4 · xH2O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies HE-NECA with a purity of ≥98% (HPLC). This is a research grade material, and we do not represent it as USP, BP, or EP.

What are the safety and handling precautions for HE-NECA?

When handling HE-NECA, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany 3.

How is HE-NECA supplied and shipped?

HE-NECA is supplied as a solid, white in colour, and typically stored at 2-8°C. TSS exports chemicals globally and ensures appropriate packaging for safe transit.