1-Pyrrolidinecarbonyl chloride
1-Pyrrolidinecarbonyl chloride (CAS: 1192-63-8) is a chemical compound with a molecular weight of 133.58. It is primarily used as a building block in chemical synthesis, particularly within the realm of heterocyclic compounds and pyrrolidine derivatives. Available from Tech Serve Solutions with a purity of 97%, it serves as a valuable reagent for researchers and manufacturers in the pharmaceutical and fine chemical industries.

Synthesis of Complex Molecules
1-Pyrrolidinecarbonyl chloride serves as a key intermediate in the multi-step synthesis of advanced organic compounds. Its reactive nature allows for its incorporation into larger molecular structures, facilitating the creation of novel chemical entities.
Pharmaceutical Intermediate
This compound is employed in the synthesis pathways for potential pharmaceutical agents. Its pyrrolidine core is a common structural motif found in various biologically active molecules, making it useful for drug discovery and development.
Research and Development
As a heterocyclic building block, 1-Pyrrolidinecarbonyl chloride is utilised in academic and industrial research laboratories for exploring new reaction methodologies and developing innovative materials or compounds.
| Molecular weight | 133.58 |
|---|---|
| Empirical formula | C5H8ClNO |
| Assay | 97% |
| Boiling point | 104-106 °C/14 mmHg(lit.) |
| Density | 1.209 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.493(lit.) |
| Storage temperature | −20°C |
| Application | 1-Pyrrolidinecarbonyl chloride was used in the synthesis of (S)-4-(2-(((benzyloxy)carbonyl)amino)-3-methoxy-3-oxopropyl)phenyl pyrrolidine-1-carboxylate1. |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 98 °C / 208.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Pyrrolidinecarbonyl chloride used for?
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1-Pyrrolidinecarbonyl chloride is used as a building block in chemical synthesis, particularly for heterocyclic compounds and pyrrolidines. It has been employed in the synthesis of complex organic molecules and pharmaceutical intermediates.
What is the CAS number and molecular formula for 1-Pyrrolidinecarbonyl chloride?
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The CAS number for 1-Pyrrolidinecarbonyl chloride is 1192-63-8, and its empirical formula is C5H8ClNO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Pyrrolidinecarbonyl chloride with an assay of 97%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 1-Pyrrolidinecarbonyl chloride be handled safely?
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1-Pyrrolidinecarbonyl chloride is classified as Danger, causing severe skin burns and eye damage (H314). Handling requires full personal protective equipment, including faceshields, full-face respirators, gloves, and goggles. Ensure adequate ventilation and use appropriate respirator filters (e.g., ABEK).
Is 1-Pyrrolidinecarbonyl chloride shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1-Pyrrolidinecarbonyl chloride.
How can I request a sample or quote for 1-Pyrrolidinecarbonyl chloride?
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Please contact Tech Serve Solutions directly through our website or sales channels to request a sample or a quotation for 1-Pyrrolidinecarbonyl chloride.
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