ABT-702 dihydrochloride
ABT-702 dihydrochloride, identified by CAS 214697-26-4 (free base), is a chemical compound with the formula C22H19BrN6O · 2HCl and a molecular weight of 536.25 g/mol. It functions as a potent and selective inhibitor of adenosine kinase (ADK). This compound is valuable in biochemical research, particularly for studying cellular energy metabolism and adenosine signaling pathways. Its specific inhibitory action makes it a key reagent for in vitro investigations.
- IUPAC
- 4-Amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2,3-d]pyrimidine
- Synonyms
- 4-Amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2,3-d]pyrimidine dihydrochloride
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Adenosine Kinase Inhibition
ABT-702 dihydrochloride is utilized as a highly selective inhibitor of adenosine kinase (ADK), an enzyme crucial for adenosine metabolism and cellular energy balance. It is employed in research to investigate the role of ADK in various physiological and pathological processes.
Cellular Metabolism Research
This compound serves as a tool for researchers studying cellular energy homeostasis and purine metabolism. By inhibiting ADK, it allows for the examination of how adenosine levels and ATP synthesis are affected in cellular systems.
Biochemical Assays
ABT-702 dihydrochloride is used in biochemical assays to characterize enzyme kinetics and screen for compounds that modulate ADK activity. Its well-defined inhibitory profile aids in the validation of experimental models.
| Molecular weight | 536.25 |
|---|---|
| Empirical formula | C22H19BrN6O · 2HCl |
| Solubility | DMSO: soluble24 mg/mLH2O: insoluble |
| Melting point | 227-245 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is ABT-702 dihydrochloride used for?
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ABT-702 dihydrochloride is used as a selective inhibitor of adenosine kinase (ADK) for biochemical and cellular research, aiding in the study of cellular energy metabolism and adenosine signaling pathways.
What is the CAS number and chemical formula for ABT-702 dihydrochloride?
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The CAS number for the free base is 214697-26-4, and the chemical formula for the dihydrochloride salt is C22H19BrN6O · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies ABT-702 dihydrochloride as a research-grade chemical. We do not represent this product as USP, BP, EP, or for use in pharmaceutical, nutraceutical, or food applications unless explicitly stated otherwise in the product specifications.
What are the safety precautions when handling ABT-702 dihydrochloride?
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When handling ABT-702 dihydrochloride, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended. Refer to the Safety Data Sheet (SDS) for comprehensive safety information.
How is ABT-702 dihydrochloride typically shipped and exported?
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ABT-702 dihydrochloride is carefully packaged and prepared for global export by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds.
How can I request a sample or quote for ABT-702 dihydrochloride?
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To request a sample or obtain a quote for ABT-702 dihydrochloride, please contact our sales department through the website or by phone, providing your contact details and the quantity required.
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