Polysorbate 80
Polysorbate 80 (CAS: 9005-65-6) is a non-ionic surfactant widely utilised for its emulsifying and solubilising properties. With an average molecular weight of 79,000, this ethoxylated sorbitan ester is an O/W emulsifier with an HLB of 15. It finds broad application in laboratory research, particularly in cell culture and biochemical assays, owing to its ability to stabilise formulations and enhance the solubility of hydrophobic compounds.
- IUPAC
- POE (20) sorbitan monooleate,Polyethylene glycol sorbitan monooleate,Polyoxyethylenesorbitan monooleate,Polysorbate 80
- Synonyms
- Polyoxyethylenesorbitan monooleatePolysorbate 80POE (20) sorbitan monooleatePolyethylene glycol sorbitan monooleateSorban MO 20
Emulsifier and Solubiliser
Polysorbate 80 functions as a key emulsifier in various formulations, enabling the mixing of immiscible liquids. Its detergent properties also aid in solubilising hydrophobic molecules for analysis or biological applications.
Cell Culture Reagent
This non-ionic surfactant is used in cell culture media to prevent cell aggregation and to aid in the solubilisation of nutrients or specific media components.
Biochemical Assays
In biochemical research, Polysorbate 80 is employed to stabilise enzymes and proteins, and to facilitate the solubilisation of membrane proteins for study.
Chromatography Applications
It serves as a component in certain chromatographic mobile phases or as a surface coating agent, aiding separation processes.
| Density | 1.07 g/cm3 at 25 °C(lit.) |
|---|---|
| Refractive index | n20/D 1.472(lit.) |
| Concentration | 10% |
| Vapour pressure | <1 mmHg (20 °C) |
| Storage temperature | 2-8°C |
| Contains / stabiliser | BHT as antioxidant |
| Impurities tested | ≤0.5 μmol/g Peroxides≤1.0 μmol/g Carbonyls≤3.0% water |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | non-ionic |
|---|---|
| Pharmacopeia | testing conforms to Pharmacopeia |
| Mol Wt | average mol wt 79,000 |
| Transition Temp | cloud point 65 °C |
| Aggregation Number | 60 |
| Cmc | 0.012 |
| Hlb | 15 |
| Hydroxyl Value | 65‑80 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Polysorbate 80 used for?
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Polysorbate 80 is used as a non-ionic surfactant, emulsifier, and solubiliser in laboratory research, cell culture, biochemical assays, and chromatography. It helps stabilise formulations and improve the solubility of hydrophobic substances.
What is the CAS number and formula for Polysorbate 80?
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The CAS number for Polysorbate 80 is 9005-65-6. The specific chemical formula is complex and represented by its structure as an ethoxylated sorbitan monooleate.
What grade and purity does Tech Serve Solutions supply for Polysorbate 80?
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Tech Serve Solutions supplies Polysorbate 80 that conforms to Pharmacopeia testing. The specific assay and grade are available upon request, and TSS does not represent this product as USP, BP, or EP grade unless explicitly stated in the product data.
How should Polysorbate 80 be handled safely?
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When handling Polysorbate 80, ensure adequate ventilation and wear appropriate personal protective equipment, including eyeshields and gloves. Refer to the Safety Data Sheet for detailed hazard information and handling procedures.
Is Polysorbate 80 a controlled substance?
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Based on the provided data, Polysorbate 80 (CAS: 9005-65-6) is not listed as a controlled substance.
How is Polysorbate 80 packaged and shipped?
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Polysorbate 80 is available for laboratory and industrial use and is carefully packaged for safe shipping and export worldwide by Tech Serve Solutions.
How can I request a quote or sample of Polysorbate 80?
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To request a quote or a sample of Polysorbate 80, please contact our sales team through the website or by phone. Our team will assist you promptly.
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