Porphobilinogen
Porphobilinogen (CAS: 487-90-1; Formula: C10H14N2O4; MW: 226.23 g/mol) is a heterocyclic organic compound and a key intermediate in the biosynthesis of tetrapyrroles, including heme and chlorophyll. It is a vital biochemical reagent primarily used in research settings for studying metabolic pathways, enzyme kinetics, and porphyrin synthesis. Supplied as a powder, it requires storage at METHyphenethylamine. -20°C for optimal stability.
- IUPAC
- 5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propanoic acid
- Synonyms
- 5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propanoic acid
Biochemical Research
Porphobilinogen serves as a crucial substrate in enzymatic studies, particularly for porphobilinogen deaminase (also known as hydroxymethylbilane synthase), an enzyme involved in the tetrapyrrole biosynthesis pathway. It is essential for investigating metabolic disorders related to porphyrin synthesis.
Cell Biology Studies
This compound is utilised in cell biology to explore cellular metabolic processes and the regulation of heme and chlorophyll production. Its role as a precursor makes it valuable for understanding the intricate mechanisms within cells.
Enzyme Assays and Substrate Analysis
As an enzyme substrate, porphobilinogen is employed in quantitative assays to measure enzyme activity and to study enzyme inhibition. Researchers use it to characterise the kinetic properties of enzymes within the tetrapyrrole pathway.
| Molecular weight | 226.23 |
|---|---|
| Empirical formula | C10H14N2O4 |
| Form | powder |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Porphobilinogen used for?
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Porphobilinogen is primarily used as a substrate in biochemical research for studying tetrapyrrole biosynthesis, enzyme kinetics, porphyrin synthesis, and metabolic pathways. It is crucial for cell biology studies investigating cellular metabolism and for enzyme assays.
What is the CAS number and chemical formula for Porphobilinogen?
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The CAS number for Porphobilinogen is 487-90-1, and its chemical formula is C10H14N2O4.
What grade and purity does Tech Serve Solutions supply for Porphobilinogen?
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Tech Serve Solutions supplies Porphobilinogen as a powder. The specific grade and purity (assay) are detailed in the product's specifications. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the verified product data. For detailed specifications, please refer to the product's technical data sheet.
What are the safety and handling precautions for Porphobilinogen?
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Porphobilinogen is classified with GHS07 symbol and a 'Warning' signal word. It is known to cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn when handling. Ensure adequate ventilation and avoid dust formation.
How is Porphobilinogen packed, shipped, and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Porphobilinogen is carefully packed to ensure stability during transit and is available for international export. Specific packaging details can be provided upon request.
How can I request a sample or quote for Porphobilinogen?
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To request a sample or a quote for Porphobilinogen (CAS: 487-90-1), please contact our sales department through the TSS website or by phone. Our team will be happy to assist you with your inquiry.
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