Potassium 4-nitrophenyl sulfate
Potassium 4-nitrophenyl sulfate (CAS: 6217-68-1; Formula: NO2C6H4OSO2OK) is a chemical reagent with a molecular weight of 257.26 g/mol. It is primarily utilised as an enzyme substrate in biochemical research and diagnostics. This compound plays a crucial role in assays involving enzymes that cleave sulfate groups, enabling the detection and quantification of enzymatic activity. Its stability and predictable reactivity make it a valuable tool for various analytical applications.
- IUPAC
- 4-Nitrophenyl sulfate potassium salt

Enzyme Substrate in Biochemical Assays
Potassium 4-nitrophenyl sulfate serves as a chromogenic substrate for enzymes such as phosphatases and sulfatases. Upon enzymatic hydrolysis, it releases 4-nitrophenol, which can be quantified spectrophotometrically, allowing for the measurement of enzyme activity.
Diagnostic Reagent
In diagnostic kits, this compound is employed to detect specific enzymatic activities in biological samples. Its use facilitates the identification of certain metabolic conditions or enzyme deficiencies through colourimetric or spectrophotometric analysis.
Research Chemical
Researchers utilise Potassium 4-nitrophenyl sulfate in studies investigating enzyme kinetics, mechanisms of action, and the development of enzyme-based assays. It is a standard reagent for exploring enzyme-catalysed reactions in various biological contexts.
| Molecular weight | 257.26 |
|---|---|
| Linear formula | NO2C6H4OSO2OK |
| Storage temperature | −20°C |
| Melting point | 246-250 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Potassium 4-nitrophenyl sulfate used for?
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Potassium 4-nitrophenyl sulfate is primarily used as an enzyme substrate in biochemical research and diagnostic assays. It is particularly useful for detecting and quantifying the activity of enzymes that cleave sulfate groups.
What are the CAS number and formula for Potassium 4-nitrophenyl sulfate?
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The CAS number for Potassium 4-nitrophenyl sulfate is 6217-68-1, and its linear formula is NO2C6H4OSO2OK.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Potassium 4-nitrophenyl sulfate as a research-grade chemical. The specific purity or assay is detailed in the product's Certificate of Analysis. Tech Serve Solutions does not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated.
What are the safety and handling recommendations for Potassium 4-nitrophenyl sulfate?
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Potassium 4-nitrophenyl sulfate requires careful handling. Personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with a WGK rating of 3 in Germany, indicating a high hazard level.
How is Potassium 4-nitrophenyl sulfate shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Potassium 4-nitrophenyl sulfate is packaged and shipped in compliance with international regulations for chemical transport. We handle all necessary export documentation for global distribution.
How can I request a sample or quote for Potassium 4-nitrophenyl sulfate?
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To request a sample or a quote for Potassium 4-nitrophenyl sulfate, please contact our sales team via the website or direct email, providing your specific requirements and shipping details.
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