7-Ethoxy-4-(trifluoromethyl)coumarin
7-Ethoxy-4-(trifluoromethyl)coumarin (CAS: 115453-82-2) is a specialized organic compound with the molecular formula C12H9F3O3 and a molecular weight of 258.19 g/mol. This fluorogenic substrate is primarily utilised in biochemical research for enzyme activity assays. Its distinct fluorescent properties make it valuable for detecting specific enzymatic reactions in various biological and chemical contexts.
- IUPAC
- Ethyl 4-(trifluoromethyl)umbelliferyl ether
- Synonyms
- Ethyl 4-(trifluoromethyl)umbelliferyl ether

Enzyme Activity Assays
Utilised as a fluorogenic substrate to monitor the activity of specific enzymes. Upon enzymatic cleavage, it releases a fluorescent product, enabling quantitative measurement of enzyme kinetics.
Biochemical Research
A key reagent in biochemical studies, particularly for investigations involving esterase or other hydrolase activities where fluorescence detection is required.
Fluorescent Probes
Serves as a fluorogenic probe, allowing for the detection and quantification of enzyme presence or activity in complex biological samples.
| Molecular weight | 258.19 |
|---|---|
| Empirical formula | C12H9F3O3 |
| Assay | ≥98% (TLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 333 nm; λem 415 nm in methanol |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7-Ethoxy-4-(trifluoromethyl)coumarin used for?
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7-Ethoxy-4-(trifluoromethyl)coumarin is primarily used as a fluorogenic substrate for enzyme activity assays in biochemical research, allowing for the detection and quantification of specific enzymatic reactions.
What is the CAS number and molecular formula for 7-Ethoxy-4-(trifluoromethyl)coumarin?
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The CAS number is 115453-82-2 and the molecular formula is C12H9F3O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 7-Ethoxy-4-(trifluoromethyl)coumarin with an assay of ≥98% (TLC). TSS does not represent this product as USP/BP/EP grade.
How should 7-Ethoxy-4-(trifluoromethyl)coumarin be handled?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store at -20°C.
Does TSS export 7-Ethoxy-4-(trifluoromethyl)coumarin?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 7-Ethoxy-4-(trifluoromethyl)coumarin.
How can I request a sample or quote for 7-Ethoxy-4-(trifluoromethyl)coumarin?
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Please contact the TSS sales team directly through the website or by phone to request a sample or obtain a quotation for 7-Ethoxy-4-(trifluoromethyl)coumarin.
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