3-(Trifluoromethyl)phenylhydrazine
3-(Trifluoromethyl)phenylhydrazine (CAS: 368-78-5) is an organic compound with the linear formula CF<sub>3</sub>C<sub>6</sub>H<sub>4</sub>NHNH<sub>2</sub> and a molecular weight of 176.14 g/mol. This hydrazine derivative serves as a valuable building block in organic synthesis, particularly in the formation of heterocyclic compounds and as a reagent in various chemical transformations. It is employed in research and development settings for creating novel molecular structures.

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules. Its reactive hydrazine group allows for diverse derivatisation and coupling reactions, facilitating the construction of various chemical scaffolds.
Heterocyclic Chemistry
A useful precursor for the synthesis of nitrogen-containing heterocyclic compounds, such as indoles and pyrazoles. These structures are prevalent in pharmaceuticals and agrochemicals.
Reagent in Chemical Research
Employed in academic and industrial research laboratories for exploring new synthetic pathways and developing novel chemical entities. Its specific functionality enables targeted chemical modifications.
| Molecular weight | 176.14 |
|---|---|
| Linear formula | CF3C6H4NHNH2 |
| Assay | 90% |
| Boiling point | 80-83 °C/9 mmHg(lit.) |
| Density | 1.348 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.504(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 107 °C / 224.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Trifluoromethyl)phenylhydrazine used for?
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3-(Trifluoromethyl)phenylhydrazine is primarily used as a building block and intermediate in organic synthesis and heterocyclic chemistry research.
What is the CAS number and formula for 3-(Trifluoromethyl)phenylhydrazine?
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The CAS number is 368-78-5 and the linear formula is CF3C6H4NHNH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Trifluoromethyl)phenylhydrazine with an assay of 90%. We do not represent this product as USP, BP, or EP grade.
What are the main hazards associated with 3-(Trifluoromethyl)phenylhydrazine?
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This compound is harmful if swallowed, in contact with skin, or if inhaled. It also causes skin irritation, serious eye irritation, and respiratory irritation. Appropriate personal protective equipment, including gloves, eyeshields, and a respirator, should be used.
How is 3-(Trifluoromethyl)phenylhydrazine packed, shipped, and exported?
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Tech Serve Solutions safely packs and prepares 3-(Trifluoromethyl)phenylhydrazine for global export in compliance with all relevant regulations.
How can I request a sample or quote for 3-(Trifluoromethyl)phenylhydrazine?
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To request a sample or quote, please contact our sales team through the website or by phone.
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