7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (CAS 76877-33-3) is a chemical compound with the molecular formula C24H22N2O4 and a molecular weight of 402.44 g/mol. This fluorescent probe is specifically designed for detecting glutathione in intact cells. Its notable advantages include high quantum yield, a good Stokes shift, and selective fluorescence only for thio derivatives, making it a valuable tool in biochemical research.
- IUPAC
- 1H-Pyrrole-2,5-dione, 1-(4-(7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl)phenyl)-,CPM
Glutathione Detection Probe
Utilised as a highly specific fluorescence probe for the quantitative detection of glutathione within intact living cells. The compound exhibits selective fluorescence only upon reaction with thio-derivatives, enabling accurate assessment of cellular glutathione levels.
Biochemical Assays
Serves as a versatile reagent in various biochemical assays requiring fluorescent labelling or detection. Its properties are advantageous for studying cellular redox states and thiol-containing biomolecules.
Cellular Imaging
Enables advanced cellular imaging techniques due to its fluorescent characteristics, allowing researchers to visualise and quantify intracellular glutathione distribution and changes.
| Molecular weight | 402.44 |
|---|---|
| Empirical formula | C24H22N2O4 |
| Assay | ≥95% (HPLC) |
| Solubility | DMSO: solublemethanol: soluble |
| Storage temperature | −20°C |
| Application | Fluorescence probe for glutathione for intact cells; specific advantages: only thio derivative fluoresces, high quantum yield and good Stokes shift |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioReagent |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin used for?
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7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (CAS 76877-33-3) is primarily used as a specific fluorescence probe for detecting glutathione in intact cells. It offers high quantum yield and a good Stokes shift, fluorescing only with thio derivatives.
What is the CAS number and chemical formula for 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin?
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The CAS number is 76877-33-3, and the empirical formula is C24H22N2O4.
What grade and purity does Tech Serve Solutions supply for 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin?
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Tech Serve Solutions supplies 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin with an assay of ≥95% (HPLC). We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
What are the safety and handling requirements for 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin?
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Users should wear appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK Germany rating of 3, indicating it is hazardous to water.
How is 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin packed, shipped, and exported?
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This chemical is typically stored at -20°C and is soluble in DMSO and methanol. TSS ensures compliant packing, shipping, and export procedures adhering to all relevant regulations for fine chemicals.
How can I request a quote or sample for 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin?
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To request a quote or sample, please contact our sales department through the TSS website or by calling our customer service line. Our team will promptly assist you with your enquiry.
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