7-Deaza-2′-deoxyguanosine 5′-triphosphate lithium salt

CAS 101515-08-6C11H17N4O13P3Biochemicals & Reagents

7-Deaza-2′-deoxyguanosine 5′-triphosphate lithium salt (CAS: 101515-08-6) is a modified nucleotide with the empirical formula C11H17N4O13P3 and a molecular weight of 506.19 g/mol. This compound is vital in molecular biology for applications requiring the prevention of secondary structure formation during DNA analysis. It is commonly supplied as a 10 mM solution in H2O and stored at -20°C.

IUPAC: −N7-dGTP,7-Deaza-dGTP

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7-Deaza-2′-deoxyguanosine 5′-triphosphate lithium salt (C11H17N4O13P3) — chemical structure, CAS 101515-08-6; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsNucleosidesNucleotidesOligonucleotides

01 /Applications

Preventing Secondary Structure Formation

The 7-deaza modification of guanosine prevents the formation of secondary structures that can occur with standard G residues during electrophoresis. This structural change circumvents sequence ambiguities in DNA analysis.

Improving Sequencing Accuracy

By avoiding the stable G-quadruplex structures, 7-Deaza-dGTP enhances the accuracy of DNA sequencing and analysis, particularly in regions rich in guanine residues.

Research and Development in Molecular Biology

This modified nucleotide is a crucial reagent for researchers in molecular biology, genomics, and biotechnology involved in advanced DNA synthesis and analysis techniques.

02 /Properties

Molecular weight	506.19
Empirical formula	C11H17N4O13P3
Concentration	10 mM in H2O
Storage temperature	−20°C
Application	G residues can form secondary structures which are not fully denatured during electrophoresis. This can lead to sequence ambiguities. 7-Deaza-G doesn′t form these secondary structures, so avoids sequence ambiguities.

03 /Identifiers & registry

CAS number

101515-08-6

MDL number

MFCD00171614

PubChem substance

24894227

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is 7-Deaza-2′-deoxyguanosine 5′-triphosphate lithium salt used for?

It is used to prevent secondary structure formation in guanosine residues during DNA analysis, thereby avoiding sequence ambiguities in techniques like DNA sequencing and electrophoresis.

What is the CAS number and formula for this compound?

The CAS number is 101515-08-6, and the empirical formula (Hill notation) is C11H17N4O13P3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product as a 10 mM solution in H2O. We do not represent it as USP, BP, or EP grade. For specific purity requirements, please contact our sales team.

What are the safety and handling considerations for this chemical?

This compound has a WGK Germany classification of 2. Handle with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet (SDS) for comprehensive safety information.

How is this chemical packed, shipped, and exported?

This chemical is typically stored at -20°C. TSS ensures compliant packing and labelling for safe domestic and international export according to relevant regulations.

How can I request a sample or quote for 7-Deaza-2′-deoxyguanosine 5′-triphosphate lithium salt?

Please contact our sales department via our website or by telephone to request a sample or a quotation. Please specify the required quantity and delivery location.