6-(Trifluoromethyl)pyridine-2-carbonyl chloride
6-(Trifluoromethyl)pyridine-2-carbonyl chloride (CAS: 1099597-77-9; C7H3ClF3NO) is a specialised organic compound with a molecular weight of 209.55 g/mol. As an acid chloride derivative of a trifluoromethyl-substituted pyridine, it serves as a valuable intermediate in organic synthesis. Its reactivity makes it suitable for introducing the 6-(trifluoromethyl)pyridine-2-carbonyl moiety into various molecules, finding utility in the development of novel chemical entities.
Organic Synthesis Intermediate
This compound acts as a key building block in multi-step organic syntheses. Its acid chloride functionality readily reacts with nucleophiles like amines, alcohols, and thiols to form amides, esters, and thioesters, respectively.
Pharmaceutical Research
It is employed in the synthesis of potential pharmaceutical agents, where the trifluoromethylpyridine scaffold can confer desirable pharmacokinetic or pharmacodynamic properties.
Agrochemical Development
The trifluoromethylpyridine moiety is present in some agrochemicals, suggesting potential applications for this compound in the research and development of new pesticides or herbicides.
Materials Science
This building block can be used in the synthesis of functional materials or ligands where the electronic or steric properties of the trifluoromethylpyridine group are beneficial.
| Molecular weight | 209.55 |
|---|---|
| Empirical formula | C7H3ClF3NO |
| Assay | 97% |
| Density | 1.450 g/mL at 25 °C |
| Refractive index | n20/D 1.473 |
| Storage temperature | −20°C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | >110 °C / >230 °F |
|---|---|
| Transport (UN / ADR) | UN 1759 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-(Trifluoromethyl)pyridine-2-carbonyl chloride used for?
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6-(Trifluoromethyl)pyridine-2-carbonyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly in the research and development of pharmaceuticals and agrochemicals.
What is the CAS number and chemical formula for 6-(Trifluoromethyl)pyridine-2-carbonyl chloride?
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The CAS number is 1099597-77-9, and the chemical formula is C7H3ClF3NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-(Trifluoromethyl)pyridine-2-carbonyl chloride with an assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 6-(Trifluoromethyl)pyridine-2-carbonyl chloride be handled and stored?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). It should be handled with appropriate personal protective equipment (P280) and stored under inert gas at -20°C.
Is 6-(Trifluoromethyl)pyridine-2-carbonyl chloride a controlled substance?
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The provided data does not indicate that 6-(Trifluoromethyl)pyridine-2-carbonyl chloride is a controlled substance.
How is this chemical packed and shipped?
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This material is shipped as UN 1759, Class 8, Packing Group II, indicating it is a corrosive solid.
How can I request a quote or sample?
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To request a quote or sample, please contact the Tech Serve Solutions sales department through the website or designated contact channels.
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