6-(Trifluoromethyl)pyridine-3-carbonyl chloride
6-(Trifluoromethyl)pyridine-3-carbonyl chloride (CAS: 358780-13-9, C7H3ClF3NO) is a heterocyclic building block supplied by Tech Serve Solutions. With a molecular weight of 209.55, this compound serves as a key intermediate in organic synthesis. Its reactive acyl chloride group and trifluoromethyl-substituted pyridine ring make it valuable for introducing this specific moiety into more complex molecules across various chemical research and development applications. Available at an assay of 97%.
- IUPAC
- 6-(Trifluoromethyl)nicotinoyl chloride

Organic Synthesis Intermediate
This compound acts as a crucial intermediate in the synthesis of diverse organic molecules. Its structure is particularly useful for introducing the 6-(trifluoromethyl)pyridine-3-carbonyl group into target compounds.
Pharmaceutical Research
It is employed in the development of novel pharmaceutical candidates. The trifluoromethylpyridine scaffold is present in various biologically active molecules, making this a valuable building block for medicinal chemists.
Agrochemical Development
The trifluoromethylpyridine moiety is also found in certain agrochemicals. This compound can be utilized in the synthesis of new pesticides, herbicides, or fungicides.
Materials Science
Potentially used in the synthesis of specialised polymers or functional materials where the electronic properties of the trifluoromethylpyridine group are advantageous.
| Molecular weight | 209.55 |
|---|---|
| Empirical formula | C7H3ClF3NO |
| Assay | 97% |
| Boiling point | 54 °C/2 mmHg(lit.) |
| Density | 1.438 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4750(lit.) |
| Storage temperature | 2-8°C |


Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 108 °C / 226.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-(Trifluoromethyl)pyridine-3-carbonyl chloride used for?
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6-(Trifluoromethyl)pyridine-3-carbonyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What are the CAS number and formula for this compound?
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The CAS number for 6-(Trifluoromethyl)pyridine-3-carbonyl chloride is 358780-13-9, and its empirical formula is C7H3ClF3NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-(Trifluoromethyl)pyridine-3-carbonyl chloride with a minimum assay of 97%. This is a technical/research grade material and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should 6-(Trifluoromethyl)pyridine-3-carbonyl chloride be handled safely?
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This compound is dangerous and should be handled with extreme care. It is corrosive and harmful if swallowed (H302-H314). Always use appropriate personal protective equipment, including eyeshields, gloves, and a type N95 respirator filter. Handle only in a well-ventilated area or fume hood. Refer to the Safety Data Sheet for full details.
Does Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or quote?
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To request a sample or a quote for 6-(Trifluoromethyl)pyridine-3-carbonyl chloride, please contact our sales team through the website or by phone.
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