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6-(Trifluoromethyl)pyridine-3-carbonyl chloride

CAS 358780-13-9C7H3ClF3NOChemical Synthesis

6-(Trifluoromethyl)pyridine-3-carbonyl chloride (CAS: 358780-13-9, C7H3ClF3NO) is a heterocyclic building block supplied by Tech Serve Solutions. With a molecular weight of 209.55, this compound serves as a key intermediate in organic synthesis. Its reactive acyl chloride group and trifluoromethyl-substituted pyridine ring make it valuable for introducing this specific moiety into more complex molecules across various chemical research and development applications. Available at an assay of 97%.

IUPAC
6-(Trifluoromethyl)nicotinoyl chloride
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6-(Trifluoromethyl)pyridine-3-carbonyl chloride (C7H3ClF3NO) — chemical structure, CAS 358780-13-9; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisHeterocyclic Building BlocksPyridines
01 /Applications

Organic Synthesis Intermediate

This compound acts as a crucial intermediate in the synthesis of diverse organic molecules. Its structure is particularly useful for introducing the 6-(trifluoromethyl)pyridine-3-carbonyl group into target compounds.

Pharmaceutical Research

It is employed in the development of novel pharmaceutical candidates. The trifluoromethylpyridine scaffold is present in various biologically active molecules, making this a valuable building block for medicinal chemists.

Agrochemical Development

The trifluoromethylpyridine moiety is also found in certain agrochemicals. This compound can be utilized in the synthesis of new pesticides, herbicides, or fungicides.

Materials Science

Potentially used in the synthesis of specialised polymers or functional materials where the electronic properties of the trifluoromethylpyridine group are advantageous.

02 /Properties
Molecular weight209.55
Empirical formulaC7H3ClF3NO
Assay97%
Boiling point54 °C/2 mmHg(lit.)
Density1.438 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.4750(lit.)
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H302Harmful if swallowed
  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Flash point108 °C / 226.4 °F
Transport (UN / ADR)UN 3265 8 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)22-34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
358780-13-9
MDL number
MFCD01862645
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 6-(Trifluoromethyl)pyridine-3-carbonyl chloride used for?

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6-(Trifluoromethyl)pyridine-3-carbonyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.

What are the CAS number and formula for this compound?

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The CAS number for 6-(Trifluoromethyl)pyridine-3-carbonyl chloride is 358780-13-9, and its empirical formula is C7H3ClF3NO.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 6-(Trifluoromethyl)pyridine-3-carbonyl chloride with a minimum assay of 97%. This is a technical/research grade material and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.

How should 6-(Trifluoromethyl)pyridine-3-carbonyl chloride be handled safely?

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This compound is dangerous and should be handled with extreme care. It is corrosive and harmful if swallowed (H302-H314). Always use appropriate personal protective equipment, including eyeshields, gloves, and a type N95 respirator filter. Handle only in a well-ventilated area or fume hood. Refer to the Safety Data Sheet for full details.

Does Tech Serve Solutions export this chemical?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.

How can I request a sample or quote?

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To request a sample or a quote for 6-(Trifluoromethyl)pyridine-3-carbonyl chloride, please contact our sales team through the website or by phone.

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