6-(Trifluoromethyl)pyridine-3-carboxaldehyde
6-(Trifluoromethyl)pyridine-3-carboxaldehyde (CAS: 386704-12-7, C7H4F3NO) is a specialised heterocyclic aldehyde with a molecular weight of 175.11 g/mol. This compound serves as a valuable building block in organic synthesis, particularly within the pharmaceutical and agrochemical industries. Its unique trifluoromethylpyridine structure allows for the introduction of fluorinated pyridine moieties into more complex molecular architectures.
- IUPAC
- 6-(Trifluoromethyl)nicotinaldehyde
- Synonyms
- 6-(Trifluoromethyl)nicotinaldehyde

Pharmaceutical Intermediate
Utilised as a key building block in the synthesis of novel pharmaceutical agents. The trifluoromethylpyridine motif is often incorporated to enhance drug properties such as metabolic stability and lipophilicity.
Agrochemical Development
Serves as a precursor for the development of new pesticides and herbicides. The incorporation of fluorine can often lead to enhanced biological activity and environmental persistence profiles.
Organic Synthesis Reagent
A versatile reagent for introducing the 6-(trifluoromethyl)pyridin-3-yl group into various organic molecules. Its aldehyde functionality readily participates in a wide range of chemical transformations.
| Molecular weight | 175.11 |
|---|---|
| Empirical formula | C7H4F3NO |
| Assay | 95% |
| Storage temperature | 2-8°C |
| Melting point | 52-56 °C |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38-43 |
| Safety statements (S) | 26-28-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-(Trifluoromethyl)pyridine-3-carboxaldehyde used for?
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This compound is primarily used as a building block in organic synthesis, particularly for creating intermediates in the pharmaceutical and agrochemical sectors.
What is the CAS number and formula for 6-(Trifluoromethyl)pyridine-3-carboxaldehyde?
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The CAS number is 386704-12-7 and the molecular formula is C7H4F3NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should 6-(Trifluoromethyl)pyridine-3-carboxaldehyde be handled safely?
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This compound is classified as Danger, with hazards including H301 (Toxic if swallowed), H315 (Causes skin irritation), H317 (May cause an allergic skin reaction), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges, is essential.
Is 6-(Trifluoromethyl)pyridine-3-carboxaldehyde a controlled substance?
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Based on the provided data, there is no indication that this substance is specifically scheduled or controlled.
How is this chemical packed and exported?
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This chemical is shipped under UN 2811, Hazard Class 6.1, Packing Group III. We are experienced global suppliers and exporters of fine chemicals.
How can I request a sample or quote for 6-(Trifluoromethyl)pyridine-3-carboxaldehyde?
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Please contact our sales team via our website or direct email to request a sample or a quotation for this product.
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