6-(Trifluoromethyl)pyridine-3-carboxylic acid

CAS 231291-22-8C7H4F3NO2Chemical Synthesis

6-(Trifluoromethyl)pyridine-3-carboxylic acid (CAS 231291-22-8) is a fluorinated heterocyclic compound with the molecular formula C7H4F3NO2 and a molecular weight of 191.11 g/mol. This building block is valuable in organic synthesis, particularly for the construction of more complex molecules. Its trifluoromethyl group and pyridine core offer unique electronic and steric properties, making it a sought-after intermediate in the development of novel chemical entities.

IUPAC: 6-(Trifluoromethyl)nicotinic acid

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6-(Trifluoromethyl)pyridine-3-carboxylic acid (C7H4F3NO2) — chemical structure, CAS 231291-22-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksChemical SynthesisHeterocyclic Building BlocksPyridines

01 /Applications

Organic Synthesis Intermediate

Serves as a key building block in multi-step organic syntheses, enabling the introduction of a trifluoromethylpyridine moiety into target molecules.

Pharmaceutical Research

Used in the development of new pharmaceutical agents, where the trifluoromethyl group can enhance metabolic stability and lipophilicity.

Agrochemical Development

Applicable in the design and synthesis of novel agrochemicals, leveraging its structural features for potential bioactivity.

Materials Science

Investigated for use in the creation of advanced materials where its electronic or structural properties may be advantageous.

02 /Properties

Molecular weight	191.11
Empirical formula	C7H4F3NO2
Assay	96%
Melting point	193-197 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

231291-22-8

MDL number

MFCD00792430

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 6-(Trifluoromethyl)pyridine-3-carboxylic acid primarily used for?

This compound is primarily used as a building block in organic synthesis, particularly in pharmaceutical and agrochemical research and development.

What is the CAS number and molecular formula?

The CAS number is 231291-22-8, and the molecular formula is C7H4F3NO2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 6-(Trifluoromethyl)pyridine-3-carboxylic acid at an assay of 96%. We do not represent this product as USP, BP, or EP grade.

What are the main safety hazards associated with this chemical?

This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It requires appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves.