6-(Trifluoromethyl)pyridine-2-carboxaldehyde
6-(Trifluoromethyl)pyridine-2-carboxaldehyde (CAS: 131747-65-4, C7H4F3NO) is a fluorinated heterocyclic building block with a molecular weight of 175.11 g/mol. This compound is valuable in organic synthesis, particularly for introducing the trifluoromethylpyridine moiety into more complex molecular structures. It serves as a key intermediate in the development of pharmaceuticals, agrochemicals, and materials science research, offering a unique combination of a pyridine ring and a trifluoromethyl group.
- IUPAC
- 6-(Trifluoromethyl)-2-pyridinecarboxaldehyde,6-(Trifluoromethyl)picolinaldehyde
- Synonyms
- 6-(Trifluoromethyl)-2-pyridinecarboxaldehyde6-(Trifluoromethyl)picolinaldehyde

Pharmaceutical Intermediates
Used in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), leveraging the unique electronic and steric properties of the trifluoromethylpyridine scaffold.
Agrochemical Development
Serves as a building block for creating new pesticides, herbicides, and fungicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
Materials Science Research
Incorporated into functional materials and polymers, potentially influencing properties such as thermal stability, optical characteristics, or electronic behaviour.
Organic Synthesis Reagent
A versatile reagent for introducing the 6-(trifluoromethyl)pyridine-2-yl group in various chemical transformations, enabling access to complex fluorinated heterocycles.
| Molecular weight | 175.11 |
|---|---|
| Empirical formula | C7H4F3NO |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Flash point | 75 °C / 167 °F |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38-43 |
| Safety statements (S) | 26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-(Trifluoromethyl)pyridine-2-carboxaldehyde used for?
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6-(Trifluoromethyl)pyridine-2-carboxaldehyde is primarily used as a building block in organic synthesis, particularly for pharmaceuticals, agrochemicals, and materials science research. It allows for the introduction of the trifluoromethylpyridine moiety into more complex molecules.
What is the CAS number and chemical formula?
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The CAS number for 6-(Trifluoromethyl)pyridine-2-carboxaldehyde is 131747-65-4, and its chemical formula is C7H4F3NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research and development purposes. The specific assay and grade are detailed on the product's Certificate of Analysis. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should 6-(Trifluoromethyl)pyridine-2-carboxaldehyde be handled safely?
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This compound is classified as Danger, with hazards including H301 (Toxic if swallowed), H315 (Causes skin irritation), H317 (May cause an allergic skin reaction), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment (gloves, eye protection, respiratory protection) in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
Is this compound regulated or a controlled substance?
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The provided data does not indicate that 6-(Trifluoromethyl)pyridine-2-carboxaldehyde is a controlled substance. However, users should always verify local regulations.
How is this chemical exported and shipped?
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This product is shipped as UN 2811, Class 6.1, Packing Group III, according to ADR regulations. Tech Serve Solutions adheres to all international shipping and export regulations for hazardous materials.
How can I request a sample or a quote?
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To request a sample or a quote for 6-(Trifluoromethyl)pyridine-2-carboxaldehyde, please contact the Tech Serve Solutions sales team via our website or listed contact details, specifying the CAS number 131747-65-4.
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