6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester
6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester (CAS: 485799-04-0), with the molecular formula C15H23BN2O3, is a key organometallic reagent. This compound serves as a versatile building block in organic synthesis, particularly in the development of novel pharmaceuticals and advanced materials. Its utility is primarily linked to cross-coupling reactions, enabling the construction of complex molecular architectures.
- IUPAC
- 1-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]morpholine
- Synonyms
- 1-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]morpholine
Suzuki-Miyaura Cross-Coupling Reactions
This boronate ester is an excellent coupling partner in Suzuki-Miyaura reactions, facilitating the formation of carbon-carbon bonds with aryl and heteroaryl halides. It is instrumental in the synthesis of biaryl and heteroaryl compounds.
Pharmaceutical Intermediate Synthesis
The compound is frequently employed in the synthesis of active pharmaceutical ingredients (APIs) and drug discovery candidates. Its pyridine and morpholine moieties offer valuable structural features for medicinal chemistry.
Materials Science
It can be used in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers, due to the electronic properties imparted by the heteroaromatic system.
Agrochemical Research
The structural motif may be incorporated into novel agrochemical compounds, contributing to the development of new pesticides and herbicides.
| Molecular weight | 290.17 |
|---|---|
| Empirical formula | C15H23BN2O3 |
| Assay | 97% |
| Melting point | 135-139 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the creation of carbon-carbon bonds. It finds application in pharmaceutical intermediate synthesis, materials science, and agrochemical research.
What are the CAS number and molecular formula?
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The CAS number is 485799-04-0 and the molecular formula is C15H23BN2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. It is supplied as a research or technical grade material and is not represented as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling precautions?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK 2 in Germany, indicating it is hazardous to water.
How is this product packed, shipped, and exported?
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Tech Serve Solutions ensures secure and compliant packaging for domestic and international shipment. The product is exported globally, adhering to all relevant regulations.
How can I request a sample or quote?
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Please contact our sales team via the website or provide your details to request a sample or a formal quotation for 6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester.
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