3,4-Dihydro-2H-pyran-6-boronic acid pinacol ester

CAS 1025707-93-0C11H19BO3Chemical Synthesis

3,4-Dihydro-2H-pyran-6-boronic acid pinacol ester (CAS: 1025707-93-0) is an organoboron compound with the molecular formula C11H19BO3 and a molecular weight of 210.08 g/mol. It serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. This stable boronate ester is frequently employed in the development of complex organic molecules and pharmaceutical intermediates, offering a reliable route to introducing the dihydropyran moiety.

IUPAC: 2-(5,6-Dihydro-4H-pyran-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Synonyms: 2-(5,6-Dihydro-4H-pyran-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

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3,4-Dihydro-2H-pyran-6-boronic acid pinacol ester (C11H19BO3) — chemical structure, CAS 1025707-93-0; Chemistry, fine chemical supplied by Tech Serve Solutions

Boronate EstersChemical SynthesisHeteroaryl Boronate EstersOrganometallic Reagents

01 /Applications

Organic Synthesis

This compound is a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds. It is used to introduce the 3,4-dihydro-2H-pyran-6-yl group into various organic frameworks.

Pharmaceutical Intermediate

It functions as a versatile intermediate in the synthesis of complex pharmaceutical agents. Its structure allows for further functionalisation in the development of new drug candidates.

Heterocyclic Chemistry

The dihydropyran ring system is prevalent in many natural products and biologically active molecules. This reagent provides a convenient method for constructing such heterocyclic structures.

02 /Properties

Molecular weight	210.08
Empirical formula	C11H19BO3
Density	1.014 g/mL at 25 °C
Storage temperature	2-8°C

03 /Safety & handling

Flash point	102 °C / 215.6 °F
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1025707-93-0

MDL number

MFCD07368233

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3,4-Dihydro-2H-pyran-6-boronic acid pinacol ester used for?

This compound is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and as an intermediate in the synthesis of pharmaceuticals and complex organic molecules.

What are the CAS number and molecular formula?

The CAS number is 1025707-93-0, and the molecular formula is C11H19BO3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical with a purity of 97%. It is suitable for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.

How should this chemical be handled and stored?

This compound is combustible and has a flash point of 102 °C (215.6 °F). It should be stored under refrigeration at 2-8 °C and handled with appropriate personal protective equipment in a well-ventilated area. It is classified as hazardous for the environment (WGK 3).

How is this product packed, shipped, and exported?

Tech Serve Solutions carefully packs and ships chemicals globally, adhering to all international regulations for the safe transport of hazardous materials.