3,4-Dihydro-2-pyridol[1,2-a]pyrimidinone

CAS 5439-14-5C8H8N2OChemical Synthesis

3,4-Dihydro-2-pyridol[1,2-a]pyrimidinone (CAS: 5439-14-5) is a chemical compound with the molecular formula C8H8N2O and a molecular weight of 148.16 g/mol. This pyrimidine derivative serves as a valuable building block in organic synthesis. It is primarily utilised as an alkylation reagent and in derivatisation reactions, particularly for gas chromatography (GC) analysis. Its well-defined structure makes it suitable for complex chemical syntheses.

Synonyms: 5439-14-5C8H8N2O

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3,4-Dihydro-2-pyridol[1,2-a]pyrimidinone (C8H8N2O) — chemical structure, CAS 5439-14-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Alkylation ReagentsAnalytical ReagentsAnalytical/ChromatographyBuilding BlocksC6 to C8Chemical SynthesisDerivatization ReagentsEsterification ReagentsHeterocyclic Building BlocksPyrimidines More...

01 /Applications

Alkylation Reagent

3,4-Dihydro-2-pyridol[1,2-a]pyrimidinone is employed as an effective alkylating agent in organic chemistry. It can introduce alkyl groups into various organic molecules, facilitating the synthesis of more complex structures.

Derivatization for GC Analysis

This compound is specifically utilised for derivatisation, particularly in gas chromatography (GC). It helps to improve the volatility and detectability of analytes, leading to more accurate and sensitive chromatographic analysis.

Heterocyclic Building Block

As a pyrimidine derivative, it functions as a key building block in the synthesis of diverse heterocyclic compounds. Its structure is amenable to further functionalisation and incorporation into larger molecular frameworks.

Chemical Synthesis Intermediate

It serves as an intermediate in multi-step chemical syntheses. Its reactivity and structural features make it a useful starting material for the development of new chemical entities in research and development settings.

02 /Properties

Molecular weight	148.16
Empirical formula	C8H8N2O
Assay	≥99.0% (NT)≥99.0%
Grade	for GC derivatization
Storage temperature	2-8°C
Melting point	185-187 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

5439-14-5

MDL number

MFCD00042798

Beilstein registry

3667723

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3,4-Dihydro-2-pyridol[1,2-a]pyrimidinone used for?

3,4-Dihydro-2-pyridol[1,2-a]pyrimidinone is used as an alkylation reagent, a derivatisation reagent for GC analysis, and a heterocyclic building block in chemical synthesis.

What is the CAS number and formula for 3,4-Dihydro-2-pyridol[1,2-a]pyrimidinone?

The CAS number is 5439-14-5, and the molecular formula is C8H8N2O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound with an assay of ≥99.0% (NT) and ≥99.0%, graded for GC derivatisation. It is not supplied as USP, BP, EP, or pharmacopoeia grade.

How should 3,4-Dihydro-2-pyridol[1,2-a]pyrimidinone be handled?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK Germany 3, indicating it is hazardous to water.